How nature synthesizes complex secondary metabolites, or natural products, can be studied
only by working within the disciplines of both chemistry and biology. Alkaloids are a complex …

Alkaloids from plants are characterised by structural diversity and bioactivity, and maintain a
privileged position in both modern and traditional medicines. In recent years, there have …

As one type of the most important alkaloids in the world, terpenoid indole alkaloids (TIAs)
show a wide range of pharmaceutical activities that are beneficial for clinical treatments …

Benzylisoquinoline alkaloids (BIAs) produced in opium poppy have been evidenced to heal
patients suffering from various diseases. They, therefore, hold an integral position in the …

Plants produce a variety of secondary metabolites, some of which are used as
pharmaceuticals or are health promoting as food components. Recent genetic studies on the …

The plant kingdom produces hundreds of thousands of specialized bioactive metabolites,
some with pharmaceutical and biotechnological importance. Their biosynthesis and function …

Research on transcriptional regulation of terpenoid indole alkaloid (TIA) biosynthesis of the
medicinal plant, Catharanthus roseus, has largely been focused on gene function and not …

Natural products have long served as both a source and inspiration for pharmaceuticals.
Modifying the structure of a natural product often improves the biological activity of the …

The effects of methyl jasmonate (MJ) dosage on terpenoid indole alkaloid (TIA) biosynthesis
in Catharanthus roseus are correlated with the relative levels of specific MJ‐responsive …

Prospects to modify alkaloid production via genetic engineering of a single or a few
enzymatic steps have been reviewed previously. 1 The aim of this contribution is to discuss …