Purpose: To investigate the role of damage-associated molecular patterns (DAMPs) in
recurrent experimental autoimmune uveitis (EAU). Methods: Recurrent EAU was induced in …

AS101 is an organotellurium compound with multifaceted immunoregulatory properties that
is remarkable for its lack of toxicity. We tested the therapeutic effect of AS101 in experimental …

Uveitis, the pathologic condition of inflammation of the uvea, frequently leads to severe
vision loss and blindness. S100A8 is a calcium-binding protein which mainly expresses in …

The pathogenic mechanisms of intraocular inflammation had not been well studied until
Wacker and his colleagues found retinal soluble antigen (S antigen) and established …

purpose. To determine whether CD4+ CD25+ T-regulatory cells (Tregs) from the eyes of rats
with recurrent (r) experimental autoimmune uveitis (EAU) were less efficient in suppressing …

purpose. To explore the role of CD137 in the pathogenesis of experimental autoimmune
uveitis (EAU) and to compare the inhibitory mechanism of anti-CD137 mAb with other …

Experimental autoimmune uveitis (EAU) in the Lewis rat has been regarded as an acute and
monophasic disease. Uveitis can be induced by immunization with retinal soluble antigen (S …

Purpose: Inflammation generates changes in the protein constituents of the aqueous humor.
Proteins that change in multiple models of uveitis may be good biomarkers of disease or …

The S100 proteins are calcium-binding proteins that are exclusively expressed in
vertebrates, where they interact with enzymes, cytoskeletal proteins, receptors, transcription …

purpose. To identify costimulatory molecules that are important in the effector phase of
experimental autoimmune uveitis (EAU). methods. EAU was induced in C57BL/6 (B6) mice …