One-carbon metabolism is a network of biological reactions that plays critical role in DNA
methylation and DNA synthesis, and in turn, facilitates the cross-talk between genetic and …

In view of growing body of evidence substantiating the role of aberrations in one-carbon
metabolism in the pathophysiology of breast cancer and lack of studies on gene–gene …

Epidemiological studies on micronutrient consumption have reported protective associations
in the incidence and/or progression of various cancer types. Supplementation with some of …

This study investigated the association between micronutrient intake and breast cancer risk
in South Korean adult women. This association was stratified according to body mass index …

Background: Single nucleotide polymorphisms (SNP) of the folate-metabolizing enzyme
methylenetetrahydrofolate reductase (MTHFR) may modify associations between folate …

Background Vitamins involved in one-carbon metabolism are hypothesized to influence
breast cancer (BC) risk. However, epidemiologic studies that examined associations …

Epidemiological evidence suggests that intake of folate and other B‐vitamins and genetic
variants in the one‐carbon metabolism pathway could influence the risk of breast cancer …

Background Micronutrients, namely vitamins and minerals, are associated with cancer
outcomes; however, their reported effects have been inconsistent across studies. We aimed …

Folate plays an important role in DNA methylation, synthesis, and repair; intake has been
associated with breast cancer. The folate-metabolizing enzyme, methylenetetrahydrofolate …

Objective: To explore the effect of peripheral blood genomic DNA methylation on the
relationship between methyl donor status and risk of breast cancer. Methods: A case-control …