Dietary folate status as well as polymorphisms in one-carbon metabolism genes may affect
the risk of breast cancer through aberrant DNA methylation and altered nucleotide synthesis …

Few studies on micronutrients and postmenopausal breast cancer have examined the
association with breast cancer characteristics. The aim of this study was to investigate the …

Abstract Methionine, folate, vitamin B6, vitamin B12, niacin, and riboflavin intakes may be
related to breast carcinogenesis. These associations may vary by breast cancer type. Using …

The interconversion of folates by the one-carbon metabolism pathway is essential for the
synthesis of precursors used in DNA synthesis, repair, and methylation. Perturbations in this …

Purpose Physical activity, a protective factor for breast cancer, increases the level of DNA
methylation. Fibroblast growth factor receptor 2 (FGFR2), a confirmed breast cancer …

Breast cancer is one of the most common malignancies in women worldwide and is
associated with a variety of risk factors. Folate and vitamin B12 are key elements of the one …

Abstract Background/Objectives Folates found in natural foods are thought to protect against
cancer. However, folic acid (FA), a synthetic form of folate used in supplements and fortified …

Background: Folate is the primary methyl donor and B vitamins are cofactors for one-carbon
metabolism that maintain DNA integrity and epigenetic signatures implicated in …

Purpose Breast cancer is more likely attributed to a combination of genetic variations and
lifestyle factors. Both one-carbon metabolism and diet-related factors could interfere with the …

Background: Few epidemiologic studies have examined very high intakes of folate and
whether consumption of nutrients involved in one-carbon metabolism is associated with …