Modification of heritability for educational attainment and fluid intelligence by socioeconomic deprivation in the UK Biobank
M Rask-Andersen, T Karlsson, WE Ek… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: Socioeconomic factors have been suggested to influence the effect of education-
and intelligence-associated genetic variants. However, results from previous studies on the …
and intelligence-associated genetic variants. However, results from previous studies on the …
[HTML][HTML] Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N= 112 151) and 24 GWAS consortia
Causes of the well-documented association between low levels of cognitive functioning and
many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain …
many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain …
[HTML][HTML] Molecular genetic contributions to socioeconomic status and intelligence
Education, socioeconomic status, and intelligence are commonly used as predictors of
health outcomes, social environment, and mortality. Education and socioeconomic status …
health outcomes, social environment, and mortality. Education and socioeconomic status …
[HTML][HTML] Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N= 112 151)
People's differences in cognitive functions are partly heritable and are associated with
important life outcomes. Previous genome-wide association (GWA) studies of cognitive …
important life outcomes. Previous genome-wide association (GWA) studies of cognitive …
[HTML][HTML] Molecular genetic contributions to social deprivation and household income in UK Biobank
Individuals with lower socio-economic status (SES) are at increased risk of physical and
mental illnesses and tend to die at an earlier age [1–3]. Explanations for the association …
mental illnesses and tend to die at an earlier age [1–3]. Explanations for the association …
[HTML][HTML] What genome-wide association studies reveal about the association between intelligence and mental health
Intelligence, as measured by standardised tests of cognitive function, such as IQ-type tests,
is predictive of psychiatric diagnosis and psychological wellbeing. Using genome-wide …
is predictive of psychiatric diagnosis and psychological wellbeing. Using genome-wide …
Genome-wide association studies establish that human intelligence is highly heritable and polygenic
General intelligence is an important human quantitative trait that accounts for much of the
variation in diverse cognitive abilities. Individual differences in intelligence are strongly …
variation in diverse cognitive abilities. Individual differences in intelligence are strongly …
[HTML][HTML] Genomic analysis of family data reveals additional genetic effects on intelligence and personality
Pedigree-based analyses of intelligence have reported that genetic differences account for
50–80% of the phenotypic variation. For personality traits these effects are smaller, with 34 …
50–80% of the phenotypic variation. For personality traits these effects are smaller, with 34 …
Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment
Cognitive deficits and reduced educational achievement are common in psychiatric illness;
understanding the genetic basis of cognitive and educational deficits may be informative …
understanding the genetic basis of cognitive and educational deficits may be informative …
Genome-wide association study of intelligence: additive effects of novel brain expressed genes
OBJECTIVE: The purpose of the present study was to identify common genetic variants that
are associated with human intelligence or general cognitive ability. METHOD: We performed …
are associated with human intelligence or general cognitive ability. METHOD: We performed …