Sir, Mutations in the pyrin gene (MEFV) cause the inflammatory disorder familial
Mediterranean fever (FMF)[1]. Most of the patients are treated with colchicine for the …

Colchicine is the treatment of choice in familial Mediterranean fever (FMF) for the prevention
of both attacks and secondary amyloidosis. The overall nonresponder rate is about 5–10 …

Objective. Familial Mediterranean fever (FMF) is a recessively inherited autoinflammatory
disorder characterized by recurrent attacks of fever and serositis. Although colchicine is the …

Familial Mediterranean fever (FMF) is the most common autoinflammatory disease
worldwide. Approximately 5–10% of patients are unresponsive to colchicine. Aim of this …

We describe a 34-year-old male patient suffering from familial Mediterranean fever and
experiencing an increase in both the frequency and severity of disease attacks, suggesting …

Familial Mediterranean fever (FMF) is a rare hereditary autoinflammatory disease,
characterized by self-limiting periodic attacks of fever associated with abdominal and chest …

ABSTRACT BACKGROUND: Up to 5% of familial Mediterranean fever (FMF) cases are
unresponsive to colchicine, through resistance, side effects and toxicity. Anakinra is an …

Objective FMF is an autoinflammatory disease of genetic origin. Colchicine is the mainstay
of treatment for the prevention of attacks and long-term complications but 5–10% of FMF …

Objective Familial Mediterranean fever (FMF) is refractory to colchicine prophylaxis in 10–
20% of patients. In a number of patient series, treatment with anakinra, an interleukin‐1 …

Familial Mediterranean fever (FMF), a recessively inherited autoinflammatory disorder, is the
prototype of a group of disorders termed systemic autoinflammatory diseases. Such …