Med 2017; 195: 120–133. http://dx. doi. org/10.1164/rccm. 201610-2075ST (2) 3) Ouellette
DR, Patel S, Girard TD, Morris PE, Schmidt GA, Truwit JD, Alhazzani W, Burns SM, Epstein …

Background This clinical practice guideline addresses six questions related to liberation
from mechanical ventilation in critically ill adults. It is the result of a collaborative effort …

Background An update of evidence-based guidelines concerning liberation from mechanical
ventilation is needed as new evidence has become available. The American College of …

Background: This clinical practice guideline addresses six questions related to liberation
from mechanical ventilation in critically ill adults. It is the result of a collaborative effort …

A substantial proportion of critically ill patients require ventilator support with the majority
requiring invasive mechanical ventilation. Timely and safe liberation from invasive …

Background: Interventions that lead to earlier liberation from mechanical ventilation can
improve patient outcomes. This guideline, a collaborative effort between the American …

3. Béduneau G, Pham T, Schortgen F, et al; WIND Study Group and the REVA Network.
Epidemiology of weaning outcome according to a new definition: the WIND study. Am J …

Objectives: Despite protocols incorporating spontaneous breathing trials, 31% of ICU
patients experience difficult or prolonged weaning from mechanical ventilation. Nonfatiguing …

Introduction Timely liberation from invasive mechanical ventilation is important to reduce the
risk of ventilator-associated complications. Once a patient is deemed ready to tolerate a …

Multiple complications associated with mechanical ventilation mandate that clinicians
expeditiously define and reverse the pathophysiologic processes that precipitate respiratory …