Interactions between adipose tissue and the immune system in health and malnutrition

FM Wensveen, S Valentić, M Šestan… - Seminars in …, 2015 - Elsevier
Adipose tissue provides the body with a storage depot of nutrients that is drained during
times of starvation and replenished when food sources are abundant. As such, it is the …

Immune and non-immune functions of adipose tissue leukocytes

WV Trim, L Lynch - Nature Reviews Immunology, 2022 - nature.com
Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …

The immune cells in adipose tissue

AW Ferrante Jr - Diabetes, Obesity and Metabolism, 2013 - Wiley Online Library
Although the pathological role of the immune system in several metabolic disorders,
including type 1 diabetes mellitus (T1DM) and Addison's disease, has long been recognized …

The role of adipokines in chronic inflammation

P Mancuso - ImmunoTargets and therapy, 2016 - Taylor & Francis
Adipose tissue has traditionally been defined as connective tissue that stores excess
calories in the form of triacylglycerol. However, the physiologic functions attributed to …

Adipose tissue inflammation: novel insight into the role of macrophages and lymphocytes

H Sell, J Eckel - Current Opinion in Clinical Nutrition & Metabolic …, 2010 - journals.lww.com
This review summarizes strong evidence for a link between the action of innate and adaptive
immune systems in adipose tissue in the context of obesity and metabolism in rodents, but …

The complex immunological and inflammatory network of adipose tissue in obesity

V Apostolopoulos, MPJ De Courten… - Molecular nutrition & …, 2016 - Wiley Online Library
A number of approaches have been utilized in the prevention, management, and treatment
of obesity, including, surgery, medication, diet, exercise, and overall lifestyle changes …

Integrated regulation of the cellular metabolism and function of immune cells in adipose tissue

Y Oishi, I Manabe - Clinical and Experimental Pharmacology …, 2016 - Wiley Online Library
Obesity is known to associate with low‐grade, sustained, systemic inflammation, which is
considered to be a key pathological basis for obesity‐associated diseases such as diabetes …

Innate immune cells in the adipose tissue

KJ Chung, M Nati, T Chavakis… - Reviews in Endocrine and …, 2018 - Springer
Immune cells are present in the adipose tissue (AT) and regulate its function. Under lean
conditions, immune cells predominantly of type 2 immunity, including eosinophils, M2-like …

Adipose tissue in obesity‐related inflammation and insulin resistance: cells, cytokines, and chemokines

K Makki, P Froguel, I Wolowczuk - … Scholarly Research Notices, 2013 - Wiley Online Library
Adipose tissue is a complex organ that comprises a wide range of cell types with diverse
energy storage, metabolic regulation, and neuroendocrine and immune functions. Because …

Adipocytes properties and crosstalk with immune system in obesity‐related inflammation

G Maurizi, L Della Guardia, A Maurizi… - Journal of cellular …, 2018 - Wiley Online Library
Obesity is a condition likely associated with several dysmetabolic conditions or worsening of
cardiovascular and other chronic disturbances. A key role in this mechanism seem to be …