Vascular endothelial growth factor A (VEGF‐A)‐induced signaling through VEGF receptor 2
(VEGFR2) regulates both physiological and pathological angiogenesis in mammals …

Members of the vascular endothelial growth factor (VEGF) family of proteins are critical
regulators of angiogenesis. VEGF concentration gradients are important for activation and …

The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …

VEGFR surface localization plays a critical role in converting extracellular VEGF signaling
towards angiogenic outcomes, and the quantitative characterization of these parameters is …

Vascular endothelial growth factor A (VEGF-A) binding to the receptor tyrosine kinase
VEGFR2 triggers multiple signal transduction pathways, which regulate endothelial cell …

The vascular endothelial growth factor (VEGF) family binds multiple endothelial cell surface
receptors. Our goal is to build comprehensive models of these interactions for the purpose of …

Vascular endothelial growth factor (VEGF) is a key mediator of angiogenesis, whose effect
on cancer growth and development is well characterized. Alternative splicing of VEGF leads …

Placental growth factor (PlGF) competes with vascular endothelial growth factor (VEGF) for
binding to VEGF receptor (VEGFR)-1 but does not bind VEGFR2. Experiments show that …

Background Vascular endothelial growth factor (VEGF) is known to be a potent promoter of
angiogenesis under both physiological and pathological conditions. Given its role in …

Vascular patterning is a key process during development and disease. The diffusive decoy
receptor sVEGFR1 (sFlt1) is a known regulator of endothelial cell behavior, yet the …