Investigations into intracellular replication and differentiation of Trypanosoma cruzi within
the mammalian host have been restricted by limitations in our ability to detect parasitized …

As Trypanosoma cruzi, the etiological agent of Chagas disease, multiplies in the cytoplasm
of nucleated host cells, infection with this parasite is highly likely to affect host cells. We …

Chronic Trypanosoma cruzi infections are typically lifelong, with small numbers of parasites
surviving in restricted tissue sites, which include the gastrointestinal tract. There is …

Trypanosoma cruzi is an obligate intracellular parasite that infects phagocytic and non-
phagocytic mammalian cells by a complex process that appears to involve several discrete …

Trypanosoma cruzi infection leads to development of chronic Chagas disease. In this article,
we provide an update on the current knowledge of the mechanisms employed by the …

T. cruzi has a complex life cycle involving four developmental stages namely, epimastigotes,
metacyclic trypomastigotes, amastigotes and bloodstream trypomastigotes. Although …

Trypanosoma cruzi is a protozoan parasite causing Chagas disease, with a complex life
cycle involving different stages in insect vectors and mammalian hosts. Amastigotes are an …

Since the discovery of Trypanosoma cruzi as the parasite that causes Chagas disease,
nearly a century ago, the details of the organism's life cycle have fascinated scientists. T …

Trypanosoma cruzi is the causative agent of Chagas disease, the most important parasitic
infection in Latin America. Despite a global research effort, there have been no significant …

The protozoan Trypanosoma cruzi is the causative agent of Chagas disease, a neglected
tropical disease that affects around 8 million people worldwide. Chagas disease can be …