P21 is an immunomodulatory protein expressed throughout the life cycle of Trypanosoma
cruzi, the etiologic agent of Chagas disease. In vitro and in vivo studies have shown that P21 …

During invasion of host cells by Trypanosoma cruzi, the parasite that causes Chagas
disease, the elongated, flagellated trypomastigotes remodel into oval amastigotes with no …

Although many Trypanosoma cruzi (T. cruzi) strains isolated from a wide range of hosts have
been characterized, there is a lack of information about biological features from vertically …

The aim of this review is to gather the current knowledge of Trypanosoma cruzi's virulence
factors described to date in an integrative way, relating these with the parasite's life cycle …

Chagas Disease, caused by the protozoan parasite Trypanosoma cruzi, affects nearly eight
million people in the world. T. cruzi is a complex taxon represented by different strains with …

Trypanosoma cruzi is a protist parasite that is the causative agent of Chagas disease, a
neglected tropical disease endemic to the Americas. T. cruzi cells are highly polarized and …

The flagellum of Trypanosomatids is an organelle that contributes to multiple functions,
including motility, cell division, and host–pathogen interaction. Trypanin was first described …

Trypanosomes are early divergent protists with distinctive features among eukaryotic cells.
Together with Trypanosoma brucei and Leishmania spp., Trypanosoma cruzi has been one …

A major contributor to treatment failure in Chagas disease, caused by infection with the
protozoan parasite Trypanosoma cruzi, is that current treatment regimens do not address the …

Although parasite entry through breaks in the skin or mucosa is one of the main routes of
natural transmission of Trypanosoma cruzi, little is known about the host cell types initially …