Cellular culture infection with Trypanosoma cruzi is a tool used to dissect the biological
mechanisms behind Chagas disease as well as to screen potential trypanocidal …

Chagas disease, caused by the protozoan Trypanosoma cruzi, presents variable clinical
course but the phenomena underlying this variability remain largely unknown. T. cruzi has a …

The year 2009 is the centennial anniversary of the original description of Chagas disease by
Carlos Chagas. During the last 100 years, several advances have occurred regarding our …

Mammalian cell invasion by the protozoan pathogen Trypanosoma cruzi is critical to its
survival in the host. To promote its entry into a wide variety of non‐professional phagocytic …

The protozoan parasite Trypanosoma cruzi, the etiologic agent of Chagas disease, is an
obligate intracellular protozoan pathogen. Overlapping mechanisms ensure successful …

Trypanosoma cruzi presents considerable genetic and protein profile polymorphism among
different parasite populations. In a previous work, our group indicated cysteine and …

Trypanosoma cruzi, the etiological agent of Chagas disease, is a protozoan parasite usually
transmitted by triatomines. As the parasite can infect all mammals and the vectors can be …

Confocal fluorescence microscopy combined with differential interference contrast imaging
of tissues from chagasic patients enabled the unequivocal identification of the parasite …

Trypanosoma cruzi is the etiological agent of American trypanosomiasis, or Chagas
disease, and is transmitted mainly by blood-sucking reduviid insects in endemic countries …

Background Trypanosoma cruzi uses several strategies to survive in different hosts. A key
step in the life-cycle of this parasite is metacyclogenesis, which involves various …