Chagas disease, an illness caused by the protozoan Trypanosoma cruzi, is clinically and
epidemiologically important in Latin America, and particularly in Brazil. This article presents …

The genome of Trypanosoma cruzi was first made available in 2005, and the intrinsic
genome complexity of this parasite has hindered high-quality genome assembly and …

Trypomastigotes, the highly motile infective forms of Trypanosoma cruzi, are capable of
infecting several cell types. Invasion occurs either by direct recruitment and fusion of …

Host manipulation is a common strategy for invading pathogens. Trypanosoma cruzi, the
causative agent of Chagas Disease, lives intracellularly within host cells. During infection …

Trypanosoma cruzi is an obligatory intracellular protozoan parasite, and it is the etiological
agent of Chagas' disease that is endemic in the Americas. In addition to humans, a wide …

Chagas disease, caused by the kinetoplastid protozoan Trypanosoma cruzi, affects millions
of people, most of them neglected populations. The different phases of the disease, the …

Trypanosoma cruzi is the etiological agent for Chagas disease, a neglected parasitic
disease in Latin America. Gene transcription control governs the eukaryotic cell replication …

The ability of the Chagas disease agent Trypanosoma cruzi to resist extended in vivo
exposure to highly effective trypanocidal compounds prompted us to explore the potential for …

Trypanosoma cruzi is the protozoan parasite causing American trypanosomiasis or Chagas
disease, a neglected parasitosis with important human health impact in Latin America. The …

Coxiella burnetii, the etiological agent of Q fever, is an obligate intracellular bacterium that
resides within acidified vacuoles with secondary lysosomal characteristics. Infective stages …