In vivo functional neurochemistry of human cortical cholinergic function during visuospatial attention

M Lindner, T Bell, S Iqbal, PG Mullins, A Christakou - PloS one, 2017 - journals.plos.org
Cortical acetylcholine is involved in key cognitive processes such as visuospatial attention.
Dysfunction in the cholinergic system has been described in a number of neuropsychiatric …

Cholinergic innervation in adult rat cerebral cortex: a quantitative immunocytochemical description

N Mechawar, C Cozzari… - Journal of Comparative …, 2000 - Wiley Online Library
A method for determining the length of acetylcholine (ACh) axons and number of ACh axon
varicosities (terminals) in brain sections immunostained for choline acetyltransferase (ChAT) …

Focal acetylcholinergic modulation of the human midcingulo‐insular network during attention: Meta‐analytic neuroimaging and behavioral evidence

S Chakraborty, SK Lee, SM Arnold… - Journal of …, 2024 - Wiley Online Library
The basal forebrain cholinergic neurons provide acetylcholine to the cortex via large
projections. Recent molecular imaging work in humans indicates that the cortical cholinergic …

Cholinergic innervation of the basal ganglia in humans and other anthropoid primates

AR Stephenson, MK Edler, JM Erwin… - Journal of …, 2017 - Wiley Online Library
Cholinergic innervation of the basal ganglia is important in learning and memory. Striatal
cholinergic neurons integrate cognitive and motivational states with behavior. Given these …

Anatomical substrates of cholinergic‐autonomic regulation in the rat

DA Ruggiero, R Giuliano, M Anwar… - Journal of …, 1990 - Wiley Online Library
Acetylcholine (ACh) plays a major role in central autonomic regulation, including the control
of arterial blood pressure (AP). Previously unknown neuroanatomic substrates of cholinergic …

Characterization of presynaptic muscarinic receptors in central cholinergic neurons

JC Szerb - Cholinergic mechanisms and psychopharmacology, 1978 - Springer
It is now well established that anticholinergic agents such as atropine increase the evoked
release of ACh from the cerebral cortex in vivo (15, 22) and from cortical slices in vitro (2, 3) …

In vitro down-regulation predicts agonist efficacy at central muscarinic cholinergic receptors

L Stoll, WE Müller - Biochemical pharmacology, 1991 - Elsevier
Agonist induced short-term down-regulation of central muscarinic cholinergic receptors in
mechanically dissociated cells of the mouse brain has been shown to predict the efficacy of …

Activation of midbrain presumed dopaminergic neurones by muscarinic cholinergic receptors: an in vivo electrophysiological study in the rat

B Gronier, K Rasmussen - British journal of pharmacology, 1998 - Wiley Online Library
Extracellular single‐unit recording and iontophoresis were used to examine the effects of
different cholinoceptor agonists and antagonists on the firing rate and firing pattern of A9 …

Development of cholinergic markers in mouse forebrain. I. Choline acetyltransferase enzyme activity and acetylcholinesterase histochemistry

CF Höhmann, FF Ebner - Developmental Brain Research, 1985 - Elsevier
Measurements of choline acetyltransferase (ChAT) activity were made during the
development of the neocortical cholinergic innervation, and correlated with the development …

The development of cholinergic neurons

K Vaca - Brain Research Reviews, 1988 - Elsevier
Motoneuron precursors acquire some principles of their spatial organization early in their
cell lineage, probably at the blastula stage. A predisposition to the cholinergic phenotype in …