[HTML][HTML] Pathogenic extracellular vesicle (EV) signaling in amyotrophic lateral sclerosis (ALS)

G Kim, X Chen, Y Yang - Neurotherapeutics, 2022 - Elsevier
Extracellular vesicles (EVs), once considered a pathway for cells to remove waste, have now
emerged as an important mechanism for intercellular communication. EVs are particularly …

Extracellular vesicles in amyotrophic lateral sclerosis

G McCluskey, KE Morrison, C Donaghy, F Rene… - Life, 2022 - mdpi.com
Amyotrophic Lateral Sclerosis is a progressive neurodegenerative disease and is the most
common adult motor neuron disease. The disease pathogenesis is complex with the …

Recent advances in extracellular vesicles in amyotrophic lateral sclerosis and emergent perspectives

GJM Afonso, C Cavaleiro, J Valero, SI Mota, E Ferreiro - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a severe and incurable neurodegenerative disease
characterized by the progressive death of motor neurons, leading to paralysis and death. It is …

Therapeutic and diagnostic potential of extracellular vesicles in amyotrophic lateral sclerosis

TJ Ellison, SL Stice, Y Yao - Extracellular Vesicle, 2023 - Elsevier
As a late-onset and fatal neurodegenerative disease that affects upper and lower motor
neurons, amyotrophic lateral sclerosis (ALS) is a difficult disease to diagnose and treat …

Emerging role of extracellular vesicles in multiple sclerosis: From cellular surrogates to pathogenic mediators and beyond

PL Palacio, ML Pleet, E Reátegui… - Journal of …, 2023 - Elsevier
Multiple Sclerosis (MS) is a chronic, inflammatory demyelinating disease of the central
nervous system (CNS) driven by a complex interplay of genetic and environmental factors …

Extracellular vesicles in neuroinflammation

G Marostica, S Gelibter, M Gironi, A Nigro… - Frontiers in cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) are a heterogenous group of membrane-bound particles that
play a pivotal role in cell–cell communication, not only participating in many physiological …

Extracellular vesicles as innovative treatment strategy for amyotrophic lateral sclerosis

K Wang, Y Li, C Ren, Y Wang, W He… - Frontiers in Cell and …, 2021 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron degenerative
disease, and it is hard to diagnose in the early stage, and treatment means are limited, and …

Potential roles of extracellular vesicles as biomarkers and a novel treatment approach in multiple sclerosis

M Gutiérrez-Fernández, F de la Cuesta… - International Journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are a heterogeneous group of bilayer membrane-wrapped
molecules that play an important role in cell-to-cell communication, participating in many …

Extracellular vesicles and amyotrophic lateral sclerosis: from misfolded protein vehicles to promising clinical biomarkers

D Gagliardi, N Bresolin, GP Comi, S Corti - Cellular and Molecular Life …, 2021 - Springer
Extracellular vesicles (EVs) are small reservoirs of different molecules and important
mediators of cell-to-cell communication. As putative vehicles of misfolded protein …

Role of extracellular vesicles in amyotrophic lateral sclerosis

D Ferrara, L Pasetto, V Bonetto, M Basso - Frontiers in neuroscience, 2018 - frontiersin.org
Amyotrophic Lateral Sclerosis (ALS) is the most common motor neuron disease in adults
and primarily targets upper and lower motor neurons. The progression of the disease is …