[引用][C] Discovery of superior enzymes by directed molecular evolution
S Brakmann - Chembiochem, 2001 - Wiley Online Library
Natural selection has created optimal catalysts that exhibit their convincing performance
even with a number of sometimes counteracting constraints. Optimal performance of enzyme …
even with a number of sometimes counteracting constraints. Optimal performance of enzyme …
Engineered enzymes for chemical production
In order to enable competitive manufacturing routes, most biocatalysts must be tailor‐made
for their processes. Enzymes from nature rarely have the combined properties necessary for …
for their processes. Enzymes from nature rarely have the combined properties necessary for …
Attempts to fill the gap between enzymatic, homogeneous, and heterogeneous catalysis
A Corma - Catalysis Reviews, 2004 - Taylor & Francis
Bio‐inspired and single site metal complex catalysts have been discussed to direct towards
a rational design of solid heterogeneous catalysts. When concepts derived from catalytic …
a rational design of solid heterogeneous catalysts. When concepts derived from catalytic …
The impact of non-cultivated biodiversity on enzyme discovery and evolution
P Lorenz, K Liebeton, F Niehaus… - Biocatalysis and …, 2003 - Taylor & Francis
The search for novel enzymes with biotechnological potential in the fine chemical, food and
feed, detergent and cosmetics industries is driven by the need to improve existing processes …
feed, detergent and cosmetics industries is driven by the need to improve existing processes …
Industrial enzyme applications
O Kirk, TV Borchert, CC Fuglsang - Current opinion in biotechnology, 2002 - Elsevier
The effective catalytic properties of enzymes have already promoted their introduction into
several industrial products and processes. Recent developments in biotechnology …
several industrial products and processes. Recent developments in biotechnology …
Application of designed enzymes in organic synthesis
GA Strohmeier, H Pichler, O May… - Chemical …, 2011 - ACS Publications
Catalysis is a key discipline in chemistry enabling clean and cost-efficient processes for a
large variety of different products and, therefore, has a strong economic impact in industry …
large variety of different products and, therefore, has a strong economic impact in industry …
Genetic optimization of metalloenzymes: enhancing enzymes for non‐natural reactions
Artificial metalloenzymes have received increasing attention over the last decade as a
possible solution to unaddressed challenges in synthetic organic chemistry. Whereas …
possible solution to unaddressed challenges in synthetic organic chemistry. Whereas …
Artificial enzymes bringing together computational design and directed evolution
B de Pina Mariz, S Carvalho, IL Batalha… - Organic & Biomolecular …, 2021 - pubs.rsc.org
Enzymes are proteins that catalyse chemical reactions and, as such, have been widely used
to facilitate a variety of natural and industrial processes, dating back to ancient times. In fact …
to facilitate a variety of natural and industrial processes, dating back to ancient times. In fact …
Catalysis through induced intramolecularity: what can be learned by mimicking enzymes with carbonyl compounds that covalently bind substrates?
R Pascal - European Journal of Organic Chemistry, 2003 - Wiley Online Library
Protein engineering and the use of catalytic antibodies have given substance to the
possibility of making artificial enzymes, whereas chemical design has provided functional …
possibility of making artificial enzymes, whereas chemical design has provided functional …
Enzyme engineering: rational redesign versus directed evolution
R Chen - Trends in biotechnology, 2001 - cell.com
Enzyme engineering is undergoing the most profound and exciting transformation in its
history 1. It promises unprecedented expansion in the scope and applications of modified or …
history 1. It promises unprecedented expansion in the scope and applications of modified or …