Covering: up to April 2004 This review discusses the achievements of directed evolution of
enzymes relevant to natural and unnatural product chemistry focusing on the period 1998 …

Enzymes have become an attractive alternative to conventional catalysts in numerous
industrial processes. However, their properties do not always meet the criteria of the …

The synergy between synthetic biology and biocatalysis is emerging as an important trend
for future sustainable processes. This book reviews all modern and novel techniques …

In the area of human-made innovations to improve the quality of life, biocatalysis has
already had a great impact and contributed enormously to a growing number of catalytic …

The design of artificial catalysts able to compete with the catalytic proficiency of enzymes is
an intense subject of research. Non-covalent interactions are thought to be involved in …

Highlights•Metal–peptide hybrids have unique potential for catalysis.•Unnatural amino acids
(UAAs) can be used to create novel hybrid catalysts.•Several methods have been developed …

Enzymatic promiscuity, namely the possibility that one active site of an enzyme can catalyze
several different chemical transformations, has been an important research field and …

Highlights•Artificial enzymes can be designed through supramolecular interactions.•The
method of designing artificial enzymes without precise design based on protein complexes …

Clean and efficient chemical reactions with complete control of stereochemistry are normal
for enzymes. Nature's supreme catalysts can teach us a great deal about designing artificial …

Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within
both industry and academia. Today, there exists a huge choice of high-tech enzymes and …