Objectives: To determine the incidence of severe hyperbilirubinaemia in the newborn, and to
identify associated clinical and demographic variables, and short-term outcomes. Design …

In the 1950s, exchange transfusion to keep the total serum bilirubin below 20mg/dl was
shown to be an effective way of preventing kernicterus in babies with erythroblastosis fetalis …

OBJECTIVE: To study if severe hyperbilirubinemia in infants with no or minor neurologic
symptoms in the neonatal period affects children's development at the age of 1 to 5 years …

The increased susceptibility to bilirubin-related brain damage in very low birth weight infants
appears to be related to the presence of antecedent pathophysiologic alterations …

The immature hepatic metabolism of bilirubin at birth is responsible for neonatal
hyperbilirubinemia, present in more than 60% of otherwise healthy infants. Icterus (or …

Severe neonatal hyperbilirubinemia can occur without apparent reason in term healthy
breast-fed infants and some develop kernicterus. The aim of our study was to assess the …

Objective To evaluate the ability of the bilirubin-induced neurologic dysfunction (BIND) score
to predict residual neurologic and auditory disability and to document the relationship of …

Grimmer I, Berger‐Jones K, Bührer C, Brandl U, Obladen M. Late neurological sequelae of
non hemolytic hyperbilirubinemia of healthy term neonates. Acta Pædiatr 1999; 88: 661‐3 …

The pathologic phenotype of severe hyperbilirubinemia in the newborn infant is primarily
due to excessive bilirubin production and/or impaired conjugation, resulting in an increased …

A review of the literature demonstrates that severe total hyperbilirubinemia (total serum
bilirubin≥ 20 mg/dL [340 µmol/L]) in some cholestatic term (≥ 37 weeks) and late-preterm …