Innate lymphoid cells (ILCs) are effectors of innate immunity and regulators of tissue
modeling. Recently identified ILC populations have a cytokine expression pattern that …

Innate lymphoid cells (ILCs) are tissue-resident lymphocytes categorized on the basis of
their core regulatory programs and the expression of signature cytokines. Human ILC3s that …

Abstract Interleukin (IL)-2 is a pleiotropic cytokine that is necessary to prevent chronic
inflammation in the gastrointestinal tract,,–. The protective effects of IL-2 involve the …

Intestinal T cells and group 3 innate lymphoid cells (ILC3 cells) control the composition of
the microbiota and gut immune responses. Within the gut, ILC3 subsets coexist that either …

Innate lymphoid cells (ILCs) are a recently characterized family of immune cells that have
critical roles in cytokine-mediated regulation of intestinal epithelial cell barrier integrity …

Human group 1 ILCs consist of at least three phenotypically distinct subsets, including NK
cells, CD127+ ILC1, and intraepithelial CD103+ ILC1. In inflamed intestinal tissues from …

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that
encompasses Crohn's disease (CD) and ulcerative colitis. The cause of IBD is unknown, but …

Background & Aims Innate lymphoid cells (ILCs) are a heterogeneous group of mucosal
inflammatory cells that participate in chronic intestinal inflammation. We investigated the role …

Group 3 innate lymphoid cells (ILC 3), defined by expression of the transcription factor
retinoid‐related orphan receptor γt, play key roles in the regulation of inflammation and …

Innate lymphoid cells (ILC) are abundant in mucosal tissues. They serve critical functions in
anti-pathogen response and tissue homeostasis. However, the heterogenous composition of …