Biomaterials to enhance antigen-specific T cell expansion for cancer immunotherapy

A Isser, NK Livingston, JP Schneck - Biomaterials, 2021 - Elsevier
T cells are often referred to as the 'guided missiles' of our immune system because of their
capacity to traffic to and accumulate at sites of infection or disease, destroy infected or …

Innate immunity and biomaterials at the nexus: friends or foes

SN Christo, KR Diener, A Bachhuka… - BioMed research …, 2015 - Wiley Online Library
Biomaterial implants are an established part of medical practice, encompassing a broad
range of devices that widely differ in function and structural composition. However, one …

[图书][B] Biomaterials and Immune Response: Complications, Mechanisms and Immunomodulation

NE Vrana - 2018 - books.google.com
The interactions of the biomaterials with the host immune system is crucial for their
functionality. This book aims to provide the reader with a better understanding of the role of …

The era of bioengineering: how will this affect the next generation of cancer immunotherapy?

M Graciotti, C Berti, HA Klok, L Kandalaft - Journal of translational …, 2017 - Springer
Background Immunotherapy consists of activating the patient's immune system to fight
cancer and has the great potential of preventing future relapses thanks to immunological …

Biomaterials innovation for next generation ex vivo immune tissue engineering

A Singh - Biomaterials, 2017 - Elsevier
Primary and secondary lymphoid organs are tissues that facilitate differentiation of B and T
cells, leading to the induction of adaptive immune responses. These organs are present in …

The role of biomaterials and scaffolds in immune responses in regenerative medicine: macrophage phenotype modulation by biomaterial properties and scaffold …

E Antmen, NE Vrana, V Hasirci - Biomaterials science, 2021 - pubs.rsc.org
Scaffolds are an integral part of the regenerative medicine field. The contact of biomaterials
with tissue, as was clearly observed over the years, induces immune reactions in a material …

Design Principles for Immunomodulatory Biomaterials

SA Oluwole, WD Weldu, K Jayaraman… - ACS applied bio …, 2024 - ACS Publications
The immune system is imperative to the survival of all biological organisms. A functional
immune system protects the organism by detecting and eliminating foreign and host …

Tailoring biomaterials for cancer immunotherapy: emerging trends and future outlook

C Wang, Y Ye, Q Hu, A Bellotti, Z Gu - Advanced materials, 2017 - Wiley Online Library
Cancer immunotherapy, as a paradigm shift in cancer treatment, has recently received
tremendous attention. The active cancer vaccination, immune checkpoint blockage (ICB) …

T cell immunoengineering with advanced biomaterials

D Delcassian, S Sattler, IE Dunlop - Integrative Biology, 2017 - academic.oup.com
Recent advances in biomaterials design offer the potential to actively control immune cell
activation and behaviour. Many human diseases, such as infections, cancer, and …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …