Biomaterial‐Based Therapeutic Delivery of Immune Cells

AA Dravid, A Singh, AJ García - Advanced Healthcare …, 2024 - Wiley Online Library
Immune cell therapy is a transformative approach used to treat a wide range of diseases
including type 1 diabetes, sickle cell disease, disorders of the hematopoietic system, and …

Biomaterial-driven immunomodulation: cell biology-based strategies to mitigate severe inflammation and sepsis

JJM Lasola, H Kamdem, MW McDaniel… - Frontiers in …, 2020 - frontiersin.org
Inflammation is an essential component of a wide variety of disease processes and
oftentimes can increase the deleterious effects of a disease. Finding ways to modulate this …

Harnessing biomaterial architecture to drive anticancer innate immunity

MA Davis, E Cho, MH Teplensky - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Immunomodulation is a powerful therapeutic approach that harnesses the body's own
immune system and reprograms it to treat diseases, such as cancer. Innate immunity is key …

Combinatorial drug delivery approaches for immunomodulation

JM Stewart, BG Keselowsky - Advanced drug delivery reviews, 2017 - Elsevier
Immunotherapy has been widely explored for applications to both augment and suppress
intrinsic host immunity. Clinical achievements have seen a number of immunotherapeutic …

Therapeutic synthetic and natural materials for immunoengineering

A Slezak, K Chang, S Hossainy, A Mansurov… - Chemical Society …, 2024 - pubs.rsc.org
Immunoengineering is a rapidly evolving field that has been driving innovations in
manipulating immune system for new treatment tools and methods. The need for materials …

Macroscale biomaterials strategies for local immunomodulation

MO Dellacherie, BR Seo, DJ Mooney - Nature Reviews Materials, 2019 - nature.com
The immune system plays key roles in tissue homeostatic and disease processes, and
manipulation of innate and adaptive immune responses is of great promise for a wide array …

Engineered materials for cancer immunotherapy

AS Cheung, DJ Mooney - Nano today, 2015 - Elsevier
Immunotherapy is a promising treatment modality for cancer as it can promote specific and
durable anti-cancer responses. However, limitations to current approaches remain …

Immune tolerance for autoimmune disease and cell transplantation

X Luo, SD Miller, LD Shea - Annual review of biomedical …, 2016 - annualreviews.org
The undesired destruction of healthy cells, either endogenous or transplanted, by the
immune system results in the loss of tissue function or limits strategies to restore tissue …

Biomaterials to enhance adoptive cell therapy

N Eckman, A Nejatfard, R Cavet… - Nature Reviews …, 2024 - nature.com
Adoptive cell therapy (ACT) harnesses the capabilities of immune cells to fight complex
diseases such as cancer. Treatment with adoptive transfer of engineered cells has led to …

Advanced biomaterials for cell‐specific modulation and restore of cancer immunotherapy

S Ruan, Y Huang, M He, H Gao - Advanced Science, 2022 - Wiley Online Library
The past decade has witnessed the explosive development of cancer immunotherapies.
Nevertheless, low immunogenicity, limited specificity, poor delivery efficiency, and off‐target …