Methods for preparing DNA-functionalized gold nanoparticles, a key reagent of bioanalytical chemistry

B Liu, J Liu - Analytical methods, 2017 - pubs.rsc.org
Gold nanoparticles (AuNPs) have excellent optical properties such as high extinction
coefficients, distance-dependent color, strong fluorescence quenching, and localized …

Instantaneous and quantitative functionalization of gold nanoparticles with thiolated DNA using a pH-assisted and surfactant-free route

X Zhang, MR Servos, J Liu - Journal of the American Chemical …, 2012 - ACS Publications
The attachment of thiolated DNA to gold nanoparticles (AuNPs) has enabled many landmark
works in nanobiotechnology. This conjugate chemistry is typically performed using a salt …

Maximizing DNA loading on a range of gold nanoparticle sizes

SJ Hurst, AKR Lytton-Jean, CA Mirkin - Analytical chemistry, 2006 - ACS Publications
We have investigated the variables that influence DNA coverage on gold nanoparticles. The
effects of salt concentration, spacer composition, nanoparticle size, and degree of sonication …

Instantaneous attachment of an ultrahigh density of nonthiolated DNA to gold nanoparticles and its applications

X Zhang, B Liu, N Dave, MR Servos, J Liu - Langmuir, 2012 - ACS Publications
The last 16 years have witnessed the landmark development of polyvalent thiolated DNA-
functionalized gold nanoparticles (AuNP's) possessing striking properties within the …

Gold nanoparticles for the development of clinical diagnosis methods

P Baptista, E Pereira, P Eaton, G Doria… - Analytical and …, 2008 - Springer
The impact of advances in nanotechnology is particularly relevant in biodiagnostics, where
nanoparticle-based assays have been developed for specific detection of bioanalytes of …

Improving colorimetric assays through protein enzyme-assisted gold nanoparticle amplification

X Xie, W Xu, X Liu - Accounts of Chemical Research, 2012 - ACS Publications
The discovery of the DNA-mediated assembly of gold nanoparticles was a great moment in
the history of science; this understanding and chemical control enabled the rational design …

DNA dissociation and degradation at gold nanoparticle surfaces

AR Herdt, SM Drawz, Y Kang, TA Taton - Colloids and Surfaces B …, 2006 - Elsevier
The instability of DNA-functionalized gold nanoparticles (Au-DNA conjugates) upon
exposure to high temperatures is characterized using fluorescence spectroscopy, gel …

Direct colorimetric detection of unamplified pathogen DNA by dextrin-capped gold nanoparticles

AM Baetsen-Young, M Vasher, LL Matta… - Biosensors and …, 2018 - Elsevier
The interaction between gold nanoparticles (AuNPs) and nucleic acids has facilitated a
variety of diagnostic applications, with further diversification of synthesis match bio …

[引用][C] Simple and rapid colorimetric biosensors based on DNA aptamer and noncrosslinking gold nanoparticle aggregation

W Zhao, W Chiuman, MA Brook, Y Li - ChemBioChem, 2007 - Wiley Online Library
Recently, gold nanoparticles (AuNPs) have emerged as novel colorimetric reporters for the
detection of various substances including DNA,[1] metal ions,[2] and proteins.[3] The …

Interface-driven hybrid materials based on DNA-functionalized gold nanoparticles

B Liu, J Liu - Matter, 2019 - cell.com
DNA-functionalized gold nanoparticles (AuNPs) are popular hybrid materials with
applications in directed assembly, biosensor development, and drug delivery. This system is …