Alzheimer's disease (AD) is a progressive neurodegenerative disease and is closely
associated with the accumulation of β-amyloid (Aβ) and neurofibrillary tangles (NFTs). Apart …

Microglial homeostasis has emerged as a critical mediator of health and disease in the
central nervous system. In their neuroprotective role as the predominant immune cells of the …

An important component of chronic neurodegenerative diseases is the generation of an
innate inflammatory response within the CNS. Microglial and astroglial cells play a key role …

Microglia–astrocyte interactions represent a delicate balance affecting neural cell functions
in health and disease. Tightly controlled to maintain homeostasis during physiological …

In the last two decades, microglia have emerged as key contributors to disease progression
in many neurological disorders, not only by exerting their classical immunological functions …

Damage-associated microglia (DAM) profiles observed in Alzheimer's disease (AD)-related
mouse models reflect an activation state that could modulate AD risk or progression. To …

In the central nervous system (CNS), glial cells, such as microglia and astrocytes, are
normally associated with support roles including contributions to energy metabolism …

Astrocytes play important roles in numerous central nervous system disorders including
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …

Neuroinflammation is considered one of the cardinal features of Alzheimer's disease (AD).
Neuritic plaques composed of amyloid β and neurofibrillary tangle-laden neurons are …

The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …