An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis

HCA Emsley, CJ Smith, CM Gavin, RF Georgiou… - Journal of …, 2003 - Elsevier
Central nervous system and peripheral inflammation is important in the responses to
ischaemic stroke, and may also predispose to its development. We aimed to identify (1) the …

Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production

HCA Emsley, CJ Smith, CM Gavin, RF Georgiou, A Vail… - BMC neurology, 2007 - Springer
Background As critical mediators of local and systemic inflammatory responses, cytokines
are produced in the brain following ischaemic stroke. Some have been detected in the …

Alterations of inflammatory cytokines in super-acute stroke patients and the potential pathogenesis

F Li, Q Ma, L Li, L Zhang, Z Yang, Y Huang… - Journal of Clinical …, 2022 - Elsevier
Background Sufficient understanding of the systemic inflammatory response after stroke will
make the therapeutic strategy targeting inflammation more feasible. Here, we aimed to …

Monocyte count at onset predicts poststroke outcomes during a 90‐day follow‐up

L Liberale, F Montecucco… - European Journal of …, 2017 - Wiley Online Library
Background Acute ischaemic stroke (AIS) triggers both systemic and neurovascular
inflammation, influencing poststroke recovery. In smokers with AIS, inflammation might be …

Temporal course of peripheral inflammation markers and indexes following acute ischemic stroke: prediction of mortality, functional outcome, and stroke-associated …

A Adiguzel, EM Arsava, MA Topcuoglu - Neurological Research, 2022 - Taylor & Francis
Background Complete blood count derived indexes such as lymphocyte-to-neutrophil ratio
(NLR) may help in predicting pneumonia and prognosis in acute stroke. However, the …

[HTML][HTML] Cytokines, brain proteins, and growth factors in acute stroke patients: A pilot study

A Zafar, M Farooqui, A Ikram, S Suriya… - Surgical neurology …, 2021 - ncbi.nlm.nih.gov
Background: Immunomodulation and cell signaling involve several cytokines, proteins, and
other mediators released in response to the trauma, inflammation, or other insults to the …

Evaluation of the inflammatory response in sera from acute ischemic stroke patients by measurement of IL-2 and IL-10

AR Nayak, RS Kashyap, HJ Purohit, D Kabra… - Inflammation …, 2009 - Springer
Objectives We compared the concentrations of the proinflammatory cytokine interleukin-2 (IL-
2) with the anti-inflammatory cytokine interleukin-10 (IL-10) in serial serum samples from …

Correction: Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke …

CJ Smith, HCA Emsley, CM Gavin… - BMC …, 2004 - bmcneurol.biomedcentral.com
Email: Craig J Smith*-csmith@ fs1. ho. man. ac. uk; Hedley CA Emsley-hemsley@ fs1. ho.
man. ac. uk; Carole M Gavin-Carole. Gavin@ srht. nhs. uk; Rachel F Georgiou-rdrennan …

Diagnostic performances of neutrophil to lymphocyte ratio and lymphocyte to monocyte ratio in acute ischemic stroke caused by cervicocranial arterial dissection

Y Yang, G Sun, S Diao, L Yang… - Journal of Clinical …, 2020 - Wiley Online Library
Background Inflammation plays an important role in the initiation and progression of
cervicocranial arterial dissection (CCAD). New inflammatory indices derived from full cell …

The impact of inflammation on the pathogenesis and prognosis of ischemic stroke

T Nakase, T Yamazaki, N Ogura, A Suzuki… - Journal of the …, 2008 - Elsevier
The inflammation plays a critical role in the stroke onset and even in the worsening of the
lesions. Therefore, the investigation of inflammatory response in the acute stage may …