Association of opioid requirement and cancer pain with survival in advanced non-small cell lung cancer

D Zylla, MA Kuskowski, K Gupta… - British journal of …, 2014 - academic.oup.com
Background Pain is associated with shorter survival in non-small cell lung cancer (NSCLC).
Lung cancer cells express opioid receptors. Opioids promote angiogenesis, tumour growth …

Opioid dose and survival of patients with incurable nonsmall cell lung cancer: a prospective cohort study

T Hasegawa, T Oguri, T Osawa, T Sawa… - Journal of palliative …, 2018 - liebertpub.com
Background: Preclinical studies show that opioids promote angiogenesis, tumor
progression, and metastasis, resulting in shorter survival. Objective: To explore whether …

Investigation of opioid use and long-term oncologic outcomes for non-small cell lung cancer patients treated with surgery

TK Oh, JH Jeon, JM Lee, MS Kim, JH Kim, H Cho… - PLoS …, 2017 - journals.plos.org
Opioids are commonly used for postoperative pain control in cancer patients. In addition to
pain control, an association between opioid use and long-term oncologic outcomes, such as …

[HTML][HTML] Effect of opioids on cancer survival in patients with chronic pain: a propensity score-matched population-based cohort study

M Sun, CL Chang, CY Lu, J Zhang, SY Wu - British Journal of Anaesthesia, 2022 - Elsevier
Background The impact of opioid analgesic use before cancer diagnosis on survival in
patients with chronic pain is unclear. Therefore, we designed a propensity score-matched …

A retrospective analysis of the effect of intraoperative opioid dose on cancer recurrence after non‐small cell lung cancer resection

JP Cata, V Keerty, D Keerty, L Feng… - Cancer …, 2014 - Wiley Online Library
Preclinical studies have demonstrated that opioid receptor agonists increase the rate of non‐
small cell lung cancer (NSCLC) growth and metastasis. Following institutional review board …

Association of increased postoperative opioid administration with non-small-cell lung cancer recurrence: a retrospective analysis

DP Maher, W Wong, PF White… - British journal of …, 2014 - academic.oup.com
Background Evidence suggests that opioid-sparing anaesthetic techniques might be
associated with increased cancer-free postoperative survival. This could be related to …

Opioids and cancer mortality

J Amaram-Davila, M Davis, A Reddy - Current treatment options in …, 2020 - Springer
Opinion statement Opioids are the gold standard for the treatment of cancer-related pain.
Preclinical studies have associated opioids with cancer progression and overall survival. In …

Pain, opioid use, and survival in hospitalized patients with advanced cancer.

FJ Brescia, RK Portenoy, M Ryan… - Journal of Clinical …, 1992 - ascopubs.org
PURPOSE Pain is a common and feared symptom for patients with incurable cancer.
Comprehensive assessment provides the foundation for effective pain management, and …

Persistent opioid use is associated with worse survival after lobectomy for stage I non-small cell lung cancer

DB Nelson, JP Cata, J Niu, KG Mitchell, AA Vaporciyan… - Pain, 2019 - journals.lww.com
1. Background Traditionally, opioids have been considered the sine qua non of treating
postsurgical pain. However, opioid use is associated with several aspects of poor health …

Is regular systemic opioid analgesia associated with shorter survival in adult patients with cancer? A systematic literature review

JW Boland, L Ziegler, EG Boland, K McDermid… - Pain, 2015 - journals.lww.com
Opioids are important in the management of pain in patients with cancer. Clinicians and
patients are sometimes concerned about the effect of opioids on survival, which might …