[HTML][HTML] Neoadjuvant and adjuvant epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy for lung cancer

H Zhai, W Zhong, X Yang, YL Wu - Translational lung cancer …, 2015 - ncbi.nlm.nih.gov
Abstract The Lung Adjuvant Cisplatin Evaluation (LACE) meta-analysis and the meta-
analysis of individual participant data reported by non-small cell lung cancer (NSCLC) Meta …

Erlotinib as Neoadjuvant Therapy in Stage IIIA (N2) EGFR Mutation‐Positive Non‐Small Cell Lung Cancer: A Prospective, Single‐Arm, Phase II Study

L Xiong, R Li, J Sun, Y Lou, W Zhang, H Bai… - The …, 2019 - academic.oup.com
Abstract Lessons Learned The findings of this prospective, single‐arm, phase II study
showed that neoadjuvant erlotinib was well tolerated and might improve the radical …

EGFR-TKIs in adjuvant treatment of lung cancer: to give or not to give?

A Milovancev, V Stojsic, B Zaric… - OncoTargets and …, 2015 - Taylor & Francis
Epidermal growth factor receptor-tyrosine-kinase inhibitors (EGFR-TKIs) brought a
significant revolution in the treatment of non-small-cell lung cancer (NSCLC). In a short …

CTONG1103: Final overall survival analysis of the randomized phase 2 trial of erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 …

YL Wu, W Zhong, KN Chen, C Chen, F Yang, XN Yang… - 2021 - ascopubs.org
8502 Background: Median Overall survival (mOS) of stage IIIA resected NSCLC was 59.4
months (m) in CTONG 1104 adj gefitinib and 26.2 m in SAKK neoadjuvant chemo trial …

[HTML][HTML] Neoadjuvant EGFR-TKI therapy for EGFR-mutant NSCLC: a systematic review and pooled analysis of five prospective clinical trials

L Sun, YJ Guo, J Song, YR Wang, SL Zhang… - Frontiers in …, 2021 - frontiersin.org
Purpose The role of neoadjuvant epidermal growth factor receptor (EGFR)-tyrosine kinase
inhibitor (TKI) targeted therapy for patients with EGFR-mutant non-small cell lung cancer …

Adjuvant Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors (TKIs) in Resected Non–Small Cell Lung Cancer (NSCLC): A Systematic Review and Meta …

J Raphael, M Vincent, G Boldt, PS Shah… - American Journal of …, 2019 - journals.lww.com
The role of adjuvant tyrosine kinase inhibitors (TKIs) in non–small cell lung cancer (NSCLC)
is not well defined. Recent randomized controlled trials showed a disease-free survival …

Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer: final overall survival analysis of the …

WZ Zhong, HH Yan, KN Chen, C Chen… - Signal transduction and …, 2023 - nature.com
EMERGING-CTONG 1103 showed improved progression-free survival (PFS) with
neoadjuvant erlotinib vs. chemotherapy for patients harbouring EGFR sensibility mutations …

[HTML][HTML] Does neoadjuvant targeted therapy provide an opportunity for resectable EGFR-mutant lung cancer: a real-world retrospective study

C Lv, Y Ma, Q Feng, F Lu, Y Chi, N Wu… - Journal of Thoracic …, 2020 - ncbi.nlm.nih.gov
Background Although neoadjuvant chemotherapy could improve survival outcome in
resectable non–small cell lung cancer (NSCLC), the efficacy of neoadjuvant targeted …

Efficacy of EGFR tyrosine kinase inhibitors in the adjuvant treatment for operable non-small cell lung cancer by a meta-analysis

Q Huang, J Li, Y Sun, R Wang, X Cheng, H Chen - Chest, 2016 - Elsevier
Background The role of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors
(TKIs) in the adjuvant treatment of non-small cell lung cancer (NSCLC) has not been well …

Efficacy and safety of adjuvant EGFR-TKIs for resected non-small cell lung cancer: a systematic review and meta-analysis based on randomized control trials

P Zhao, H Zhen, H Zhao, L Zhao, B Cao - BMC cancer, 2022 - Springer
Background Postoperative adjuvant cisplatin-based chemotherapy had been the standard
care in patients with completely resected high-risk stage IB to IIIA non-small cell lung cancer …