Here, we report an indispensable role for spindle assembly checkpoint (SAC) component
CaMad2p in the survival and virulence of Candida albicans in mice. We hypothesized that …

Saccharomyces cerevisiae Spa2p is a component of polarisome that controls cell polarity.
Here, we have characterized the role of its homologue, CaSpa2p, in the polarized growth in …

We have analysed the effect of RAD52 deletion in several aspects of the cell biology of
Candida albicans. Cultures of rad52Δ strains exhibited slow growth and contained abundant …

Genome rearrangements, a common feature of Candida albicans isolates, are often
associated with the acquisition of antifungal drug resistance. In Saccharomyces cerevisiae …

ABSTRACT A fungus-specific outer kinetochore complex, the Dam1 complex, is essential in
Saccharomyces cerevisiae, nonessential in fission yeast, and absent from metazoans. The …

Treatments that perturb DNA synthesis or mitosis will activate checkpoints that prevent cell
cycle progression and cell proliferation. In yeast‐form cells of the fungal pathogen Candida …

The budding yeast Candida albicans is one of the most significant fungal pathogens
worldwide. It proliferates in two distinct cell types: blastopores and filaments. Only cells that …

Morphogenesis in the fungal pathogen Candida albicans is an important virulence-
determining factor, as a dimorphic switch between yeast and hyphal growth forms can …

Candida albicans is an opportunistic human pathogen, and its pathogenicity is associated
with hyphal formation. Previous studies have shown that at neutral-to-alkaline pH, hyphal …

In response to genotoxic stress (GS), C andida albicans can undergo polarized growth and
massive genome rearrangements including loss‐of‐heterozygosity (LOH) events. We …