Abstract Hypericum perforatum [St. John's wort (SJW)] is known to cause a drug interaction
with the substrates of cytochrome P450 (P450, CYP) isoforms, mainly CYP3A. This study …

St. John's wort (Hypericum perforatum) is a popular over-the-counter dietary supplement
and a herbal antidepressant that has been implicated in drug interactions with substrates of …

Aims. We previously reported the effect of St John's wort (Hypericum perforatum)
standardised extract LI 160 on the activities of cytochrome P450 2C6, 2D2 and 3As …

This investigation was designed to determine the ability of St. John's wort (SJW), a readily
available antidepressant, to induce various hepatic drug metabolizing enzymes. SJW (140 …

Background St John's wort (Hypericum perforatum) is a popular over‐the‐counter dietary
supplement and herbal remedy that has been implicated in drug interactions with substrates …

St. John's wort extract (SJW)(Hypericum perforatum L.) is among the most commonly used
herbal medications in the United States. The predominance of clinical reports indicates that …

Aims To investigate the influence of St. John's wort (SJW) on CYP3A4, CYP1A2, CYP2D6, N‐
acetyltransferase 2 (NAT2), and xanthine oxidase (XO) activities in healthy males and …

Hydroxygenkwanin (HGK), a natural flavonoid extracted from the buds of Daphne genkwa
Sieb. et Zucc.(Thymelaeaceae), possesses a wide range of pharmacological activities …

Background Administration of quercetin (QR) has shown several health benefits in clinical
and pre-clinical studies. Objective This study investigates the effect of dietary doses of QR …

Ruta graveolens (the common rue) has been used for various therapeutic purposes,
including relief of rheumatism and treatment of circulatory disorder. To elucidate the effects …