The use of RNA interference (RNAi) is spreading rapidly to nearly every aspect of
biomedical research. The gene silencing capability of RNAi is being used to study individual …

Silencing specific gene expression by RNA interference (RNAi) has rapidly become a
standard tool for the reverse genetic analysis of gene functions. It also has tremendous …

RNA interference (RNAi) is a natural cellular process that effects post-transcriptional gene
silencing in eukaryotic systems. Small interfering RNA (siRNA) molecules are the key …

Gene therapy is a promising tool for the treatment of human diseases that cannot be cured
by rational therapies. The major limitation for the use of small interfering RNA (siRNA), both …

Small interfering RNA (siRNA) is a powerful tool for modulating gene expression by RNA
interference (RNAi). Duplex RNA oligonucleotides induce cleavage of homologous target …

RNA interference (RNAi) has been regarded as a revolutionary tool for manipulating target
biological processes as well as an emerging and promising therapeutic strategy. In contrast …

Introduction: RNA interference is a sequence-specific gene silencing phenomenon in which
small interfering RNAs (siRNAs) can trigger gene transcriptional and post-transcriptional …

Gene silencing using RNA-interference, first described in mammalian systems almost a
decade ago, is revolutionizing therapeutic target validation efforts both in vitro and in vivo …

Sequence-specific gene silencing using small interfering RNA (siRNA) provides a potent
and specific method for gene expression, thus is now being evaluated in clinical trials as a …

RNA interference (RNAi) is a post-transcriptional gene-silencing mechanism that involves
the degradation of messenger RNA in a highly sequence-specific manner. Double-stranded …