[HTML][HTML] Immunotherapy based on dendritic cell-targeted/-derived extracellular vesicles—a novel strategy for enhancement of the anti-tumor immune response
O Markov, A Oshchepkova, N Mironova - Frontiers in pharmacology, 2019 - frontiersin.org
Dendritic cell (DC)-based anti-tumor vaccines have great potential for the treatment of
cancer. To date, a large number of clinical trials involving DC-based vaccines have been …
cancer. To date, a large number of clinical trials involving DC-based vaccines have been …
[HTML][HTML] Exosomes from antigen-pulsed dendritic cells induce stronger antigen-specific immune responses than microvesicles in vivo
CJE Wahlund, G Güclüler, S Hiltbrunner… - Scientific reports, 2017 - nature.com
Extracellular vesicles (EV), including exosomes and microvesicles (MV), represent a rapidly
expanding field of research with diagnostic and therapeutic applications. Although many …
expanding field of research with diagnostic and therapeutic applications. Although many …
[HTML][HTML] Exosomes and immune response in cancer: friends or foes?
FM Barros, F Carneiro, JC Machado… - Frontiers in …, 2018 - frontiersin.org
Exosomes are a type of extracellular vesicle whose study has grown exponentially in recent
years. This led to the understanding that these structures, far from being inert waste by …
years. This led to the understanding that these structures, far from being inert waste by …
Immature dendritic cell-derived exosomes: a promise subcellular vaccine for autoimmunity
W Yin, S Ouyang, Y Li, B Xiao, H Yang - Inflammation, 2013 - Springer
Abstract Exosomes, 60–90-nm-sized vesicles, are produced by a large number of cell types,
including tumor cells, neurons, astrocytes, hemocytes, intestinal epithelial cells, and so on …
including tumor cells, neurons, astrocytes, hemocytes, intestinal epithelial cells, and so on …
Extracellular vesicles as antigen carriers for novel vaccination avenues
Antigen delivery has always been a challenge in scientific practice of vaccine formulation.
Yet, mammalian extracellular vesicles (EVs) or bacterial membrane vesicles (MVs) provide …
Yet, mammalian extracellular vesicles (EVs) or bacterial membrane vesicles (MVs) provide …
[HTML][HTML] Exosome-based immunotherapy: a promising approach for cancer treatment
Z Xu, S Zeng, Z Gong, Y Yan - Molecular cancer, 2020 - Springer
In the era of the rapid development of cancer immunotherapy, there is a high level of interest
in the application of cell-released small vesicles that stimulate the immune system. As cell …
in the application of cell-released small vesicles that stimulate the immune system. As cell …
[HTML][HTML] Therapeutic prospects of extracellular vesicles in cancer treatment
Extracellular vesicles (EVs) are released by all cells within the tumor microenvironment,
such as endothelial cells, tumor-associated fibroblasts, pericytes, and immune system cells …
such as endothelial cells, tumor-associated fibroblasts, pericytes, and immune system cells …
Harnessing the exosome-induced immune response for cancer immunotherapy
U Gehrmann, TI Näslund, S Hiltbrunner… - Seminars in Cancer …, 2014 - Elsevier
In recent years exosomes have emerged as potent stimulators of immune responses and as
agents for cancer therapy. Exosomes can carry a broad variety of immunostimulatory …
agents for cancer therapy. Exosomes can carry a broad variety of immunostimulatory …
New insights into the biological impacts of immune cell-derived exosomes within the tumor environment
M Shen, X Ren - Cancer letters, 2018 - Elsevier
Exosomes are a group of nano-sized membrane vesicles that transfer proteins, nucleic
acids, and lipids to nearby and faraway cells, playing an important role in the intercellular …
acids, and lipids to nearby and faraway cells, playing an important role in the intercellular …
Dendritic cell–derived exosomes need to activate both T and B cells to induce antitumor immunity
TI Näslund, U Gehrmann, KR Qazi… - The Journal of …, 2013 - journals.aai.org
Exosomes are secreted membrane nanovesicles of endosomal origin and are considered
potential cancer vaccine vectors. Phase I clinical trials have been successfully conducted …
potential cancer vaccine vectors. Phase I clinical trials have been successfully conducted …