Alzheimer's disease (AD) is the most common neurodegenerative disease in the elderly.
Recently, genome-wide association studies (GWAS) have been used to investigate AD …

Introduction Genetic associations for endophenotypes of Alzheimer's disease (AD) in
cognitive stages preceding AD have not been thoroughly evaluated. Methods We conducted …

Whether novel risk variants of Alzheimer's disease (AD) identified through genome-wide
association studies also influence magnetic resonance imaging-based intermediate …

Objective: Recent genome-wide association studies (GWAS) of late-onset Alzheimer
disease (LOAD) identified 9 novel risk loci. Discovery of functional variants within genes at …

Genome-wide association studies (GWAS) have discovered numerous genomic loci
associated with Alzheimer's disease (AD), yet the causal genes and variants remain …

Background Genome-wide association studies demonstrate that Alzheimer's disease (AD)
has a highly polygenic architecture, where thousands of independent genetic variants …

It is estimated that the impact of related genes on the risk of Alzheimer's disease (AD) is
nearly 70%. Identifying candidate causal genes can help treatment and diagnosis. The …

Introduction Variability exists in the disease trajectories of Alzheimer's disease (AD) patients.
We performed a genome‐wide association study to examine rate of cognitive decline (ROD) …

Objective Alzheimer's disease (AD) is a neurodegenerative disorder for which more than 20
genetic loci have been implicated to date. However, studies demonstrate not all genetic …

Abstract Background Until now, Mendelian randomization (MR) studies have investigated
the causal association of risk factors with Alzheimer's disease (AD) using large-scale AD …