Novel plasma peptide markers involved in the pathology of CKD identified using mass spectrometric approach

PR Gajjala, H Bruck, H Noels, G Heinze… - Journal of Molecular …, 2019 - Springer
Chronic kidney disease (CKD) may progress to end-stage renal disease (ESRD) at different
pace. Early markers of disease progression could facilitate and improve patient …

Urine Peptidome Analysis Identifies Common and Stage-Specific Markers in Early Versus Advanced CKD

S Hobson, E Mavrogeorgis, T He, J Siwy, T Ebert… - Proteomes, 2023 - mdpi.com
Given the pathophysiological continuum of chronic kidney disease (CKD), different
molecular determinants affecting progression may be associated with distinct disease …

Urinary protein and peptide markers in chronic kidney disease

N Chebotareva, A Vinogradov, V McDonnell… - International journal of …, 2021 - mdpi.com
Chronic kidney disease (CKD) is a non-specific type of kidney disease that causes a gradual
decline in kidney function (from months to years). CKD is a significant risk factor for death …

Urinary peptidomic biomarkers in kidney diseases

V Sirolli, L Pieroni, L Di Liberato, A Urbani… - International journal of …, 2019 - mdpi.com
In order to effectively develop personalized medicine for kidney diseases we urgently need
to develop highly accurate biomarkers for use in the clinic, since current biomarkers of …

Recent advances in urinary peptide and proteomic biomarkers in chronic kidney disease: a systematic review

L Catanese, J Siwy, H Mischak, R Wendt… - International Journal of …, 2023 - mdpi.com
Biomarker development, improvement, and clinical implementation in the context of kidney
disease have been a central focus of biomedical research for decades. To this point, only …

Value of urine peptides in assessing kidney and cardiovascular disease

A Latosinska, J Siwy, S Faguer, J Beige… - PROTEOMICS …, 2021 - Wiley Online Library
Urinary peptides gained significant attention as potential biomarkers especially in the
context of kidney and cardiovascular disease. In this manuscript the recent literature since …

Understanding glomerular diseases through proteomics

E Mavrogeorgis, H Mischak, J Beige… - Expert Review of …, 2021 - Taylor & Francis
Introduction Chronic kidney disease is avery common and complex chronic disease.
Uncovering the pathological patterns of CKD on the molecular level of bio-fluids and tissue …

PeptiCKDdb—peptide-and protein-centric database for the investigation of genesis and progression of chronic kidney disease

M Krochmal, M Fernandes, S Filip, C Pontillo, H Husi… - Database, 2016 - academic.oup.com
The peptiCKDdb is a publicly available database platform dedicated to support research in
the field of chronic kidney disease (CKD) through identification of novel biomarkers and …

Urinary peptide biomarker panel associated with an improvement in estimated glomerular filtration rate in chronic kidney disease patients

K Markoska, M Pejchinovski, C Pontillo… - Nephrology Dialysis …, 2018 - academic.oup.com
Background An improvement in the glomerular filtration rate (GFR) of chronic kidney disease
patients has been an underestimated clinical outcome. Although this may be considered as …

Clinical proteomics in kidney disease as an exponential technology: heading towards the disruptive phase

MD Sanchez-Niño, AB Sanz, AM Ramos… - Clinical kidney …, 2017 - academic.oup.com
Exponential technologies double in power or processing speed every year, whereas their
cost halves. Deception and disruption are two key stages in the development of exponential …