Infiltration of intramuscular adipose tissue impairs skeletal muscle contraction

NK Biltz, KH Collins, KC Shen… - The Journal of …, 2020 - Wiley Online Library
Key points Muscle infiltration with adipose tissue (IMAT) is common and associated with loss
of skeletal muscle strength and physical function across a diverse set of pathologies …

Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans

S Sachs, S Zarini, DE Kahn… - American Journal …, 2019 - journals.physiology.org
Intermuscular adipose tissue (IMAT) is negatively related to insulin sensitivity, but a causal
role of IMAT in the development of insulin resistance is unknown. IMAT was sampled in …

Short‐term disuse promotes fatty acid infiltration into skeletal muscle

AF Pagano, T Brioche, C Arc‐Chagnaud… - Journal of cachexia …, 2018 - Wiley Online Library
Background Many physiological and/or pathological conditions lead to muscle
deconditioning, a well‐described phenomenon characterized by a loss of strength and …

Intermuscular fat: a review of the consequences and causes

O Addison, RL Marcus, PC LaStayo… - International journal of …, 2014 - Wiley Online Library
Muscle's structural composition is an important factor underlying muscle strength and
physical function in older adults. There is an increasing amount of research to support the …

Excessive adipose tissue infiltration in skeletal muscle in individuals with obesity, diabetes mellitus, and peripheral neuropathy: association with performance and …

TN Hilton, LJ Tuttle, KL Bohnert, MJ Mueller… - Physical …, 2008 - academic.oup.com
Background and Purpose The primary purpose of this study was to report differences in calf
intermuscular adipose tissue (IMAT), muscle strength (peak torque), power, and physical …

Intermuscular adipose tissue in metabolic disease

BH Goodpaster, BC Bergman, AM Brennan… - Nature Reviews …, 2023 - nature.com
Intermuscular adipose tissue (IMAT) is a distinct adipose depot described in early reports as
a 'fatty replacement'or 'muscle fat infiltration'that was linked to ageing and neuromuscular …

Intermuscular adipose tissue is muscle specific and associated with poor functional performance

LJ Tuttle, DR Sinacore, MJ Mueller - Journal of aging research, 2012 - Wiley Online Library
Purpose. People with obesity, diabetes, and peripheral neuropathy have high levels of
intermuscular adipose tissue (IMAT) volume which has been inversely related to physical …

Relationship between intermuscular adipose tissue infiltration and myostatin before and after aerobic exercise training

AR Konopka, CA Wolff, MK Suer… - American Journal of …, 2018 - journals.physiology.org
Intermuscular adipose tissue (IMAT) is associated with impaired skeletal muscle contractile
and metabolic function. Myostatin and downstream signaling proteins such as cyclin …

[HTML][HTML] Intermuscular adipose tissue: a brief review of etiology, association with physical function and weight loss in older adults

DL Waters - Annals of geriatric medicine and research, 2019 - ncbi.nlm.nih.gov
Adipose tissue redistributes during aging resulting in increased intermuscular adipose
tissue (IMAT), intramuscular, and intramyocellular lipid while subcutaneous fat decreases …

Intramuscular adipose tissue and central activation in older adults

Y Yoshida, RL Marcus, PC Lastayo - Muscle & nerve, 2012 - Wiley Online Library
Introduction: Intramuscular adipose tissue (IMAT) is a potential contributor to declining force
production and may be related to impaired central activation; therefore, the purpose of this …