Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle

JH Han, OS Kwon, JH Chung, KH Cho, HC Eun… - Journal of …, 2004 - Elsevier
Background: Minoxidil has been widely used to treat androgenetic alopecia, but little is
known about its pharmacological activity or about the identity of its target cells in hair …

Minoxidil activates β-catenin pathway in human dermal papilla cells: a possible explanation for its anagen prolongation effect

MH Kwack, BM Kang, MK Kim, JC Kim… - Journal of dermatological …, 2011 - Elsevier
BACKGROUND: It is believed that the length of the actively growing phase of the anagen
hair cycle mainly contributes to hair length. Recent studies showed that maintenance of β …

[HTML][HTML] Minoxidil promotes hair growth through stimulation of growth factor release from adipose-derived stem cells

N Choi, S Shin, SU Song, JH Sung - International journal of molecular …, 2018 - mdpi.com
Minoxidil directly promotes hair growth via the stimulation of dermal papilla (DP) and
epithelial cells. Alternatively, there is little evidence for indirect promotion of hair growth via …

Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells

Lachgar, Charveron, Gall, Bonafe - British Journal of …, 1998 - Wiley Online Library
The hair follicle dermal papilla which controls hair growth, is characterized in the anagen
phase by a highly developed vascular network. We have demonstrated in a previous study …

The effect of topical minoxidil on hair follicular cycles of rats

O Mori, H Uno - The Journal of dermatology, 1990 - Wiley Online Library
To explore an easily accessible and reproducible model for examining the effect of minoxidil
on hair growth, we studied the effect of minoxidil on the natural hair cycles of rats from birth …

Minoxidil: mechanisms of action on hair growth

AG Messenger, J Rundegren - British journal of dermatology, 2004 - academic.oup.com
We have known for over 30 years that minoxidil stimulates hair growth, yet our
understanding of its mechanism of action on the hair follicle is very limited. In animal studies …

Minoxidil stimulates mouse vibrissae follicles in organ culture

AE Buhl, DJ Waldon, TT Kawabe, JM Holland - Journal of investigative …, 1989 - Elsevier
Minoxidil, a potent vasodilator, stimulates the growth of terminal hair from vellus or
miniaturized follicles in balding scalp. To study minoxidil's action on isolated follicles we …

Use of topical minoxidil therapy for androgenetic alopecia in women

JP JACOBS, CA SZPUNAR… - International journal of …, 1993 - Wiley Online Library
Background. Androgenetic alopecia is the most common cause of hair loss in men and
women. Androgenetic alopecia in women begins as a diffuse and progressive thinning of …

Direct effects of minoxidil on epidermal cells in culture

RL Cohen, MEAF Alves, VC Weiss, DP West… - Journal of investigative …, 1984 - Elsevier
Minoxidil, a potent antihypertensive agent, induces generalized hypertrichosis when
administered systemically, or localized hair regrowth when applied topically to sites of …

Minoxidil and its use in hair disorders: a review

P Suchonwanit, S Thammarucha… - Drug design …, 2019 - Taylor & Francis
Minoxidil was first introduced as an antihypertensive medication and the discovery of its
common adverse event, hypertrichosis, led to the development of a topical formulation for …