Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis …

H Yu, L Zheng, L Yin, L Xu, Y Qi, X Han, Y Xu… - International …, 2014 - Elsevier
The present study was to investigate the effects and possible mechanisms of the total
saponins from Dioscorea nipponica Makino (TSDN) against CCl 4-induced hepato-toxicity in …

Hepatoprotective Activity of the Total Saponins from Actinidia valvata Dunn Root against Carbon Tetrachloride‐Induced Liver Damage in Mice

L Qu, H Xin, G Zheng, Y Su… - … Based Complementary and …, 2012 - Wiley Online Library
The protective activity of the total saponins from Actinidia valvata Dunn root (TSAV) was
studied against carbon‐tetrachloride‐(CCl4‐) induced acute liver injury in mice. Mice were …

Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice

D Dong, S Zhang, L Yin, X Tang, Y Xu, X Han… - Food and chemical …, 2013 - Elsevier
Saponins are the major chemicals from Rosa laevigata Michx fruit. However, there have no
papers to report the activities of the natural product against liver damage. In the present …

Protective effect of Trillium tschonoskii saponin on CCl4-induced acute liver injury of rats through apoptosis inhibition

H Wu, Y Qiu, Z Shu, X Zhang, R Li, S Liu… - Canadian journal of …, 2016 - cdnsciencepub.com
To explore hepatoprotective role and underlying mechanisms of Trillium tschonoskii Maxim
(TTM), 36 rats were randomly divided into control, CCl4-induced liver injury model, and …

[HTML][HTML] Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury by inhibiting oxidative stress and NLRP3 inflammasome activation in the …

L Lin, R Que, Y Shen, Y Chen… - Molecular medicine …, 2018 - spandidos-publications.com
Saikosaponin‑d (SSd) the primary active component of triterpene saponin derived from
Bupleurum falcatum L., possesses anti‑inflammatory and antioxidant properties. The present …

[HTML][HTML] Madecassoside prevents acute liver failure in LPS/D-GalN-induced mice by inhibiting p38/NF-κB and activating Nrf2/HO-1 signaling

W Wang, L Wu, Q Li, Z Zhang, L Xu, C Lin, L Gao… - Biomedicine & …, 2018 - Elsevier
Madecassoside (MA), a triterpenoid saponin isolated from Centella asiatica, exerts various
pharmacological activities including antioxidative and anti-inflammatory effects. The aim of …

Protective effect of saponins derived from the roots of Platycodon grandiflorum against carbon tetrachloride induced hepatotoxicity in mice

KJ Lee, JH Choi, HG Kim, EH Han, YP Hwang… - Food and Chemical …, 2008 - Elsevier
The purpose of this study was to investigate the protective effects of the saponins isolated
from the root of Platycodi Radix (Changkil saponins: CKS) on carbon tetrachloride (CCl4) …

Hepatoprotective effects of total saponins isolated from Taraphochlamys affinis against carbon tetrachloride induced liver injury in rats

QF Huang, SJ Zhang, L Zheng, M He, RB Huang… - Food and Chemical …, 2012 - Elsevier
In this study, rats were orally treated with the total saponins of Taraphochlamys affinis
(TSTA) daily with administration of CCl4 twice a week for 8weeks. Compared to the normal …

The protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in …

YL Wu, XC Feng, LH Lian, YZ Jiang, JX Nan - Journal of …, 2010 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: This study examined the protective effects of
total saponins from Ornithogalum saundersiae (Liliaceae) on d-galactosamine (d-GalN) and …

A novel type lavandulyl flavonoid from Sophora flavescens as potential anti-hepatic injury agent that inhibit TLR2/NF-κB signaling pathway

Y Lin, XJ Chen, JJ Li, L He, YR Yang, F Zhong… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacology relevance Sophora flavescens Aiton, was a crucial source of
Traditional Chinese Medicine (TCM) that has benefited human health for hundreds of years …