Extracts of Dracocephalum tanguticum Maxim Ameliorate Acute Alcoholic Liver Disease via Regulating Transcription Factors in Mice

M Guo, L Gu, H Hui, X Li, L Jin - Frontiers in Pharmacology, 2022 - frontiersin.org
Alcoholic liver disease (ALD) caused by excessive drinking is a health and economic
concern worldwide. Given the high morbidity, mortality, and the progressive nature of ALD …

Investigation on inhibitory and apoptosis-inducing effects of saponins from Tribulus terrestris on hepatoma cell line BEL-7402

B Sun, W Qu, X Zhang, H Yang… - China Journal of …, 2004 - pesquisa.bvsalud.org
ABSTRACT< p>< b> OBJECTIVE</b> To investigate the inhibitory and apoptosis-inducing
effects of saponins from Tribulus terrestris (STT) on liver cancer cell line BEL-7402.</p>< …

Effects of astragalus (ASI, SK) on experimental liver injury

YD Zhang, JP Shen, SH Zhu, DK Huang… - Yao xue xue bao …, 1992 - europepmc.org
The saponins (ASI, SK) used in this study was extracted from the root of Astragalus
membranaceous Bge and Astragalus sieversianus Pull. ASI and SK were found to protect …

Protective effect of diosgenin on LPS/D-Gal-induced acute liver failure in C57BL/6 mice

SM Mohamadi-Zarch, T Baluchnejadmojarad… - Microbial …, 2020 - Elsevier
Acute liver failure (ALF) is a deadly clinical syndrome, which leads to a rapid loss of normal
liver function. Diosgenin is a natural steroidal sapogenin found in various plant families …

Aqueous extract from Aconitum carmichaelii Debeaux reduces liver injury in rats via regulation of HMGB1/TLR4/NF-ΚB/caspase-3 and PCNA signaling pathways

JX Luo, Y Zhang, XY Hu, G Chen, XY Liu… - Journal of …, 2016 - Elsevier
Abstract Ethnopharmacological relevance Aconitum carmichaelii Debeaux is a well-known
Chinese herb that has been used to treat liver diseases for many years in China. We …

Beta-sitosterol and its derivatives repress lipopolysaccharide/d-galactosamine-induced acute hepatic injury by inhibiting the oxidation and inflammation in mice

Y Yin, X Liu, J Liu, E Cai, H Zhu, H Li, L Zhang… - Bioorganic & Medicinal …, 2018 - Elsevier
Beta-sitosterol (Sit) widely exists in natural plants, is classed as phytosterol and known as
the “key of life”. Most pharmacological studies and clinical applications are limited because …

Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice

J Mao, M Yi, R Wang, Y Huang, M Chen - Frontiers in Pharmacology, 2018 - frontiersin.org
Costunolide, a sesquiterpene isolated from Vladimiria souliei (Franch.) Ling, is known to
exhibit anti-inflammatory, anti-viral, and anti-tumor activities. However, the effects of …

[HTML][HTML] Extract of Jasminum grandiflorum L. alleviates CCl4-induced liver injury by decreasing inflammation, oxidative stress and hepatic CYP2E1 expression in mice

L Sun, Y Zhang, S Wen, Q Li, R Chen, X Lai… - Biomedicine & …, 2022 - Elsevier
Jasminum grandiflorum L.(JG) is a medicinal plant containing many bioactive ingredients.
Herein, we analyzed the effects of four different extracts and two compounds of JG on acute …

The protective effect of Esculentoside A on experimental acute liver injury in mice

F Zhang, X Wang, X Qiu, J Wang, H Fang, Z Wang… - PloS one, 2014 - journals.plos.org
Inflammatory response and oxidative stress are considered to play an important role in the
development of acute liver injury induced by carbon tetrachloride (CCl4) and galactosamine …

Platycodin D exerts anti-tumor efficacy in H22 tumor-bearing mice via improving immune function and inducing apoptosis

W Li, YH Tian, Y Liu, Z Wang, S Tang… - The Journal of …, 2016 - jstage.jst.go.jp
Platycodin D (PD), a major saponin derived and isolated from the roots of Platycodon
grandiflorum, exerts potent growth inhibition and strong cytotoxicity against various cancer …