The potential protective effect of Commelina nudiflora L. against carbon tetrachloride (CCl4)-induced hepatotoxicity in rats, mediated by suppression of oxidative …

MD Shah, UJ D'souza, M Iqbal - Environmental health and preventive …, 2017 - Springer
Background This study aims to assess the hepatoprotective potential of Commelina
nudiflora against CCl 4-induced hepatic injury in rats. Method Antioxidant activities were …

Protective effect of tormentic acid from Potentilla chinensis against lipopolysaccharide/D-galactosamine induced fulminant hepatic failure in mice

X Lin, S Zhang, R Huang, S Tan, S Liang, X Wu… - International …, 2014 - Elsevier
A compound was isolated from Potentilla chinensis, and it was identified as tormentic acid
(TA) based on its physicochemical properties and spectral data. The hepatoprotective effect …

Diosgenin induces apoptosis in HepG2 cells through generation of reactive oxygen species and mitochondrial pathway

DS Kim, BK Jeon, YE Lee, WH Woo… - Evidence‐Based …, 2012 - Wiley Online Library
Diosgenin, a naturally occurring steroid saponin found abundantly in legumes and yams, is
a precursor of various synthetic steroidal drugs. Diosgenin is studied for the mechanism of …

[HTML][HTML] Aralia saponin A isolated from Achyranthes bidentata Bl. ameliorates LPS/D-GalN induced acute liver injury via SPHK1/S1P/S1PR1 pathway in vivo and in …

M Zeng, A Feng, L Wang, K Li, J Zhou - International Immunopharmacology, 2023 - Elsevier
Objective Acute liver injury (ALI) refers to a disease in which the liver is affected by factors
such as chemical substances, alcohol, and virus infection in a short time, resulting in …

[HTML][HTML] Protective effect of lyophilized sapodilla (Manilkara zapota) fruit extract against CCl4-induced liver damage in rats

ST Alrashood, AK Al-Asmari, AK Alotaibi… - Saudi Journal of …, 2020 - Elsevier
The tropical fruit sapodilla (Manilkara zapota syn. Achras zapota) is a rich source of
nutrients, minerals and a myriad of bioactive phytochemicals such as flavonoids and …

Preventive effect of flavonoids from Wushan Shencha (Malus doumeri leaves) on CCl4‐induced liver injury

K Zhu, G Huang, J Xie, X Zhou, J Mu… - Food Science & …, 2019 - Wiley Online Library
Abstract Wushan Shencha (Malus doumeri leaf) is a unique tea‐like drink. Herein, the effect
of flavonoids from Wushan Shencha (FWSSC) on carbon tetrachloride‐induced liver injury …

Protective Effects of Flavone from Tamarix aphylla against CCl4-Induced Liver Injury in Mice Mediated by Suppression of Oxidative Stress, Apoptosis and …

B El-Aarag, A Khairy, SAM Khalifa… - International journal of …, 2019 - mdpi.com
The current study aimed to investigate, for the first time, the beneficial effects of 3, 5-
dihydroxy-4′, 7-dimethoxyflavone isolated from Tamarix aphylla L. against liver injury in …

Hepatoprotective effects of vicenin-2 and scolymoside through the modulation of inflammatory pathways

IC Lee, JS Bae - Journal of natural medicines, 2020 - Springer
The aim of this study was to investigate the effects of two structurally related flavonoids found
in Cyclopia subternata, vicenin-2 (VCN) and scolymoside (SCL) on lipopolysaccharide …

[HTML][HTML] Protective effect of Salvia miltiorrhiza and Carthamus tinctorius extract against lipopolysaccharide-induced liver injury

LN Gao, K Yan, YL Cui, GW Fan… - World Journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To investigate the hepatoprotective effects and mechanisms of an extract of Salvia
miltiorrhiza and Carthamus tinctorius in vivo. METHODS: C57BL/6J mice were randomly …

Protective effects of maternal administration of total saponins of Codonopsis pilosula in the mice offspring following diarrhea: role of immune function, antioxidant …

J Li, Y Sun, N Yang, H Zhang, Y Hu, H Wang… - … Science and Pollution …, 2023 - Springer
Total saponins of Codonopsis (TSC) are a kind of critical bioactive substances in
Codonopsis, which have anti-inflammatory, antioxidant, anti-ulcer, immunomodulatory …