OBJECTIVES: A population-based study was performed to characterise the genotype and
phenotype of drug-resistant tuberculosis (TB) in the year 2004–2005 in two Chinese rural …

Background The aim of this study was to investigate the molecular characteristics of
isoniazid resistant Mycobacterium tuberculosis (MTB), as well as its contribution to the …

Objectives Multidrug-resistant tuberculosis (MDR-TB) is a major public-health problem in
China. However, there is little information on the molecular characterisation of clinical MDR …

Drug-resistant tuberculosis (DR-TB), especially multidrug-resistant tuberculosis (MDR-TB),
is a serious medical and societal problem in China. The purpose of this study was to …

Objectives To explore the prevalence, risk and genetic characteristics of drug-resistant
tuberculosis (TB) from a tertiary care TB hospital in China. Patients and methods We carried …

To determine the prevalence and molecular characteristics of drug-resistant tuberculosis in
Hunan province, drug susceptibility testing and spoligotyping methods were performed …

Drug-resistant tuberculosis (DR-TB) is still a major public health concern in South Africa.
Mutations in M. tuberculosis can cause varying levels of phenotypic resistance to anti-TB …

Objective: To assess the molecular mechanism of rifampin (RMP) resistance in clinical
strains of Mycobacterium tuberculosis. Design: The molecular nature of a part of the rpoB …

Since rifampicin resistance is a surrogate marker for multidrug-resistant Mycobacterium
tuberculosis (MDRTB), the present study aimed to investigate rpoB mutations conferring …

Objective This study analyzed drug resistance and mutations profiles in Mycobacterium
tuberculosis isolates in a surveillance site in Huairou District, Beijing, China. Methods The …