The influence of the cholesterol microenvironment in tissue sections on molecular ionization efficiencies and distributions in ToF-SIMS

AFM Altelaar, J van Minnen, RMA Heeren… - Applied surface …, 2006 - Elsevier
High-resolution images of cholesterol were obtained from Lymnaea stagnalis nervous tissue
using metal-assisted (MetA) time-of-flight secondary ion mass spectrometry (ToF-SIMS). The …

MS/MS methodology to improve subcellular mapping of cholesterol using TOF-SIMS

PD Piehowski, AJ Carado, ME Kurczy… - Analytical …, 2008 - ACS Publications
Time-of-flight secondary ion mass spectrometry (TOF-SIMS) can be utilized to map the
distribution of various molecules on a surface with submicrometer resolution. Much of its …

Mass spectrometric imaging of lipids in brain tissue

P Sjövall, J Lausmaa, B Johansson - Analytical chemistry, 2004 - ACS Publications
The spatial distributions of various specific lipids in freeze-dried mouse brain sections were
monitored using time-of-flight secondary ion mass spectrometry (TOF-SIMS). Mouse brain …

Localization of lipids in freeze-dried mouse brain sections by imaging TOF-SIMS

P Sjövall, B Johansson, J Lausmaa - Applied Surface Science, 2006 - Elsevier
Imaging time-of-flight-secondary ion mass spectrometry (TOF-SIMS) was used to analyse
the lateral distributions of lipids on the surface of freeze-dried mouse brain sections. Tissue …

Lipid imaging with time-of-flight secondary ion mass spectrometry (ToF-SIMS)

MK Passarelli, N Winograd - … et Biophysica Acta (BBA)-Molecular and Cell …, 2011 - Elsevier
Fundamental advances in secondary ion mass spectrometry (SIMS) now allow for the
examination and characterization of lipids directly from biological materials. The successful …

ToF‐SIMS imaging of lipids in cell membranes

B Johansson - Surface and Interface Analysis: An International …, 2006 - Wiley Online Library
Secondary ion mass spectrometry (SIMS) has been in use in biomedical imaging for more
than three decades and has resulted in some important biomedical discoveries. However …

[HTML][HTML] Molecular depth profiling on rat brain tissue sections prepared using different sampling methods

HK Shon, SH Kim, S Yoon, CY Shin, TG Lee - Biointerphases, 2018 - pubs.aip.org
Brain imaging using time-of-flight secondary ion mass spectrometry (ToF-SIMS) has been
reported to produce the distorted biomolecular distributions due to the cholesterol-induced …

Imaging lipids with secondary ion mass spectrometry

ML Kraft, HA Klitzing - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2014 - Elsevier
This review discusses the application of time-of-flight secondary ion mass spectrometry (TOF-
SIMS) and magnetic sector SIMS with high lateral resolution performed on a Cameca …

Micrometric molecular histology of lipids by mass spectrometry imaging

D Touboul, O Laprévote, A Brunelle - Current opinion in chemical biology, 2011 - Elsevier
Time-Of-Flight Secondary Ion Mass Spectrometry is compared to other mass spectrometry
imaging techniques, and recent improvements of the experimental methods, driven by …

Time-of-flight secondary ion mass spectrometry imaging of subcellular lipid heterogeneity: Poisson counting and spatial resolution

PD Piehowski, AM Davey, ME Kurczy… - Analytical …, 2009 - ACS Publications
Mass spectrometric imaging is a powerful tool to interrogate biological complexity. One such
technique, time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging, has been …