STUDY QUESTION Does supplementation with co-enzyme Q10 (CoQ10) improve the
oocyte mitochondrial abnormalities associated with obesity in mice? SUMMARY ANSWER …

Acquiring oocyte competence requires optimal mitochondrial function and adequate ATP
levels. In this context, CoQ10 supplementation may improve human oocyte quality and …

Female reproductive capacity declines dramatically in the fourth decade of life as a result of
an age‐related decrease in oocyte quality and quantity. The primary causes of reproductive …

Over the past four decades, due to cultural and social changes, women in the developed
world have significantly delayed childbirth. This trend is even worse for patients who attend …

STUDY QUESTION Can diet normalization or a calorie-restricted diet for 2 or 4 weeks be
used as a preconception care intervention (PCCI) in Western-type diet-induced obese Swiss …

Female infertility and pregnancy maintenance are associate with various factors, including
quantity and quality of oocytes, genital inflammation, endometriosis, and other diseases …

In vitro maturation (IVM) can impair the balance between antioxidant capacity and oxidative
stress, and jeopardize embryo development by increasing oxidative stress, reducing energy …

Obesity adversely affects reproduction and results in oocyte defects in both mice and
humans. In the present study we used a mouse model to examine whether the adverse …

Environmental stress-induced alterations in oocyte mitochondria are suggested to
deleteriously affect developmental competence of the ovarian pool of oocytes. We examined …

A single missense mutation at position 159 of coenzyme Q9 (COQ9)(G→ A; rs109301586)
has been associated with genetic variation in fertility in Holstein cattle, with the A allele …