Isothermal heat conduction microcalorimetry was used to evaluate chemical stability of a
solid drug in tablets. A variety of mixtures were compressed to flat faced tablets of 300 mg …

Preformulation is the first step in the rational development of dosage form of a drug
substance and it is defined as an investigation of physical chemical properties of a drug …

Abstract Triprolidine hydrochloride (C 19 H 22 N 2· HCl· H 2 O)(TPH) is a well-known
antihistamine drug which is reported as being photosensitive. The thermal stabilities of TPH …

The thermal analytical study of venlafaxine hydrochloride, a third generation antidepressant,
was investigated using thermogravimetry (TG) and differential scanning calorimetry (DSC) …

Resumo Thermogravimetry (TG), derivative thermogravimetry (DTG) and differential
scanning calorimetry (DSC) were techniques used in this work to study thermal behavior of …

Abstract Development and validation of analytical methods of captopril tablets have been
carried out by absorbance method and area under the curve method by UV-Vis …

Application of thermogravimetry (TG) alone to study compatibility/incompatibility of active
pharmaceutical ingredients (APIs) with excipients yields to misleading results due to …

Tableting on an industrial scale is characterized by an increase in temperature, which is
dependent on numerous factors. The aim of this study was to examine the glass transition …

Thermal analysis is an essential analytical tool in development of new formulations as well
as to study the interaction between drugs and excipients. This work aims to investigate the …

The purpose of the present work was to study the compatibility of metronidazole with
different pharmaceutical excipients (hydroxypropyl methylcellulose, poly (ethylene oxide) …