Clostridioides difficile causes a range of debilitating intestinal symptoms that may be fatal. It
is particularly problematic as a hospital-acquired infection, causing significant costs to the …

Abstract Recurrent Clostridioides (formerly Clostridium) difficile infection (rCDI) is common,
and patients who have had one recurrence are more likely to have multiple recurrences …

Introduction Clostridioides difficile infection (CDI) is a major healthcare problem in the
developed world, and effective management of recurrent infection remains one of the …

Clostridium difficile (C. difficile) is rapidly becoming one of the most prevalent health care–
associated bacterial infections in the developed world. The emergence of new, more virulent …

In the past two years an enormous amount of molecular, genetic, metabolomic and
mechanistic data on the host-bacterium interaction, a healthy gut microbiota and a possible …

Clostridioides difficile infection (CDI) is one of the most common and severe nosocomial
infections worldwide. It can also affect healthy individuals in the community. The incidence of …

Despite intense international attention and efforts to reduce its incidence, Clostridium difficile
infection (CDI) remains a significant concern for patients, clinicians, and healthcare …

Background: Clostridioides difficile (C. difficile) is a spore-forming bacterial species that
ubiquitously exists in the environment. Colonization by C. difficile is highly prevalent in …

Antibiotic-associated diarrhoea is among the most common adverse events related to
antibiotic use. Most cases are mild, but Clostridium difficile infection causes a spectrum of …

Oral vancomycin and metronidazole, though they are the therapeutic choice for
Clostridioides difficile infections (CDIs), also markedly disturb microbiota, leading to a …