Many complex diseases or traits are the results of both genetic and environmental factors.
The environmental factors affect the human body by modifying its epigenetics, which …

With approximately 38 million people living with HIV/AIDS globally, and a further 1.5 million
new global infections per year, it is imperative that we advance our understanding of all …

Background Previous epigenome-wide association studies have shown that HIV infection
can disrupt the host DNA methylation landscape. However, it remains unclear how …

Background and methods: Host genomic alterations are closely related to dysfunction of
CD4+ T lymphocytes in the HIV–host interplay. However, the roles of aberrant DNA …

Alteration of DNA methylation in mammalian cells could be elicited by many factors,
including viral infections [1]. HIV has shown the ability to interact with host cellular factors to …

Epigenetic control of human immunodeficiency virus-1 (HIV-1) genes is critical for viral
integration and latency. However, epigenetic changes in the HIV-1-infected host genome …

The molecular mechanisms underlying HIV-induced inflammation, which persists even
during effective long-term treatment, remain incompletely defined. Here, we studied …

DNA methylation is one of the epigenetic modifications that configures gene transcription
programs. This study describes the DNA methylation profile of HIV-infected individuals with …

HIV-1 disrupts the host epigenetic landscape with consequences for disease pathogenesis,
viral persistence, and HIV-associated comorbidities. Here, we examined how soon after …

Epigenetic modifications refer to a number of biological processes which alter the structure
of chromatin and its transcriptional activity such as DNA methylation and histone post …