Cancer prevention: a new era beyond cyclooxygenase-2
B Rigas, K Kashfi - Journal of Pharmacology and Experimental …, 2005 - ASPET
The seminal epidemiological observation that nonsteroidal anti-inflammatory drugs
(NSAIDs) prevent colon and possibly other cancers has spurred novel approaches to cancer …
(NSAIDs) prevent colon and possibly other cancers has spurred novel approaches to cancer …
Is COX-2 a 'collateral'target in cancer prevention?
K Kashfi, B Rigas - Biochemical society transactions, 2005 - portlandpress.com
NSAIDs (non-steroidal anti-inflammatory drugs) prevent colon and other cancers. The fact
that NSAIDs inhibit the eicosanoid pathway prompted mechanistic drug-developmental work …
that NSAIDs inhibit the eicosanoid pathway prompted mechanistic drug-developmental work …
Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention
K Kashfi, B Rigas - Biochemical pharmacology, 2005 - Elsevier
Chemoprevention represents a highly promising approach for the control of cancer. That
nonsteroidal anti-inflammatory drugs (NSAIDs) prevent colon and other cancers has led to …
nonsteroidal anti-inflammatory drugs (NSAIDs) prevent colon and other cancers has led to …
Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
RA Gupta, RN DuBois - Nature Reviews Cancer, 2001 - nature.com
Population-based studies have established that long-term intake of non-steroidal anti-
inflammatory drugs (NSAIDs), compounds that inhibit the enzymatic activity of …
inflammatory drugs (NSAIDs), compounds that inhibit the enzymatic activity of …
Prevention of colorectal cancer through the use of COX-2 selective inhibitors
RM Peek - Cancer chemotherapy and pharmacology, 2004 - Springer
Colorectal cancer is a major cause of morbidity and mortality accounting for an estimated
550,000 deaths annually worldwide. Colonic neoplasia develops in a stepwise fashion …
550,000 deaths annually worldwide. Colonic neoplasia develops in a stepwise fashion …
Role of cyclooxygenase-2 in pathogenesis and prevention of colorectal cancer
E Hahn, S Kraus, N Arber - Digestive Diseases, 2010 - karger.com
Chemoprevention of colorectal cancer is a promising science that has particular importance
due to the limited success of current treatments for most advanced common malignancies …
due to the limited success of current treatments for most advanced common malignancies …
COX-2 inhibitors in cancer treatment and prevention, a recent development
XC Xu - Anti-cancer drugs, 2002 - journals.lww.com
Epidemiological and experimental studies have demonstrated the effect of non-steroidal anti-
inflammatory drugs (NSAIDs) in the prevention of human cancers. NSAIDs block …
inflammatory drugs (NSAIDs) in the prevention of human cancers. NSAIDs block …
Prevention of colorectal cancer: Tumor progression, chemoprevention, and COX–2 inhibition
RS Bresalier - Gastroenterology, 2000 - Elsevier
Chemoprevention refers to the use of natural or synthetic agents to reverse, suppress, or
prevent progression or recurrence of cancer. Colorectal cancers result from complex …
prevent progression or recurrence of cancer. Colorectal cancers result from complex …
COX-2 inhibition in clinical cancer prevention.
PM Lynch - Oncology (Williston Park, NY), 2001 - europepmc.org
Colorectal cancer is an excellent model for studying cancer prevention by means of
secondary (eg, polypectomy to remove a precursor adenoma) and primary …
secondary (eg, polypectomy to remove a precursor adenoma) and primary …
Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung
RE Harris - Inflammopharmacology, 2009 - Springer
The existing epidemiologic literature was comprehensively reviewed to retrieve all
epidemiologic studies (case control and cohort studies) that examined exposure to …
epidemiologic studies (case control and cohort studies) that examined exposure to …