Determination of some local anesthetics in human serum by gas chromatography with solid-phase extraction

M Baniceru, O Croitoru, SM Popescu - Journal of pharmaceutical and …, 2004 - Elsevier
A method of analysis based on solid-phase extraction coupled with capillary gas
chromatographic system for determination of mepivacaine, bupivacaine and lidocaine from …

Simultaneous determination of local anesthetics including ester-type anesthetics in human plasma and urine by gas chromatography–mass spectrometry with solid …

T Ohshima, T Takayasu - … of Chromatography B: Biomedical Sciences and …, 1999 - Elsevier
The present study describes the simultaneous determination of seven different kinds of local
anesthetics and one metabolite by GC–MS with solid-state extraction: Mepivacaine …

High-performance liquid chromatographic method for an automated determination of local anaesthetics in human plasma

J Drewe, S Rufer, J Huwyler, E Küsters - Journal of Chromatography B …, 1997 - Elsevier
A method is described that allows the rapid and precise determination of the local
anaesthetics bupivacaine and etidocaine from biological fluids. This method uses a fully …

Simultaneous determination of procaine, lidocaine, ropivacaine, tetracaine and bupivacaine in human plasma by high-performance liquid chromatography

W Qin, Z Jiao, M Zhong, X Shi, J Zhang, Z Li… - … of Chromatography B, 2010 - Elsevier
A simple and sensitive high-performance liquid chromatography with ultraviolet detection
(HPLC-UV) method has been developed and validated for simultaneous quantification of …

Gas chromatographic study of some local anesthetics

M Culea, N Palibroda, Z Moldovan, AD Abraham… - Chromatographia, 1989 - Springer
A sensitive capillary gas chromatographic method is described for the simultaneous
determination of lidocaine, tetracaine, procaine and dibucaine. The method was applied to …

Gas-liquid chromatographic determination and pharmacological studies of six clinically-used local anesthetics.

OW Lau, K Chan, YC Wong - Methods and findings in experimental …, 1991 - europepmc.org
A gas-liquid chromatographic method was developed for the simultaneous assay of six local
anesthetics, including amethocaine, bupivacaine, etidocaine, lignocaine, mepivacaine and …

An experimental design approach to selecting the optimum LC conditions for the determination of local anaesthetics

A Dincel, NE Basci - Chromatographia, 2007 - Springer
A sensitive high performance liquid chromatographic (HPLC) method has been developed
and validated for the simultaneous determination of four local anaesthetics: lidocaine …

[引用][C] Sensitive determination of bupivacaine in human plasma by high-performance liquid chromatography

HC Michaelis, W Geng, GF Kahl, H Foth - Journal of Chromatography B …, 1990 - Elsevier
Bupivacaine hydrochloride is an amide-type local anaesthetic, which is used to provide intra-
and postoperative epidural anaesthesia, eg in orthopaedics, abdominal surgery and …

Simultaneous determination of bupivacaine, mepivacain, prilocaine and ropivacain in human serum by liquid chromatography–tandem mass spectrometry

A Koehler, R Oertel, W Kirch - Journal of Chromatography A, 2005 - Elsevier
A liquid chromatography–tandem mass spectrometric (LC–MS-MS) method with a rapid and
simple sample preparation was developed and validated for the simultaneous determination …

Determination of local anaesthetics in body fluids by gas chromatography with surface ionization detection

H Hattori, S Yamamoto, T Yamada, O Suzuki - Journal of Chromatography B …, 1991 - Elsevier
Ten local anaesthetics were tested for their detection by gas chromatography (GC)—surface
ionization detection (SID). Lidocaine, mepivacaine and bupivacaine were detected with the …