Highly active antiretroviral treatment initiated early in the course of symptomatic primary HIV-1 infection: results of the ANRS 053 trial

B Hoen, B Dumon, M Harzic, A Venet… - The Journal of …, 1999 - academic.oup.com
Highly active antiretroviral treatment (HAART) was given early to 64 patients with
symptomatic primary human immunodeficiency virus (HIV)-1 infection. At the time of …

Initiation of Highly Active Antiretroviral Therapy at CD4+ T Lymphocyte Counts of >350 cells/mm3: Disease Progression, Treatment Durability, and Drug Toxicity

TR Sterling, RE Chaisson… - Clinical infectious …, 2003 - academic.oup.com
We compared clinical disease progression in 159 human immunodeficiency virus (HIV)-
infected persons for whom highly active antiretroviral therapy (HAART) was initiated when …

Short-course antiretroviral therapy in primary HIV infection

SPARTAC Trial Investigators - New England Journal of Medicine, 2013 - Mass Medical Soc
Background Short-course antiretroviral therapy (ART) in primary human immunodeficiency
virus (HIV) infection may delay disease progression but has not been adequately evaluated …

Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: a prospective cohort study

B Ledergerber, M Egger, M Opravil, A Telenti… - The Lancet, 1999 - thelancet.com
Background The efficacy of highly active antiretroviral therapy (HAART) in suppression of
HIV-1 is well documented. We investigated virological and clinical outcomes of HAART in …

Highly active antiretroviral therapy (HAART) for the treatment of infection with human immunodeficiency virus type 1

RW Shafer, DA Vuitton - Biomedicine & pharmacotherapy, 1999 - Elsevier
Highly active antiretroviral therapy (HAART) refers to a broad category of treatment regimens
usually comprised of three or more antiretroviral drugs that, in previously untreated HIV-1 …

Antiretroviral therapy in 1999 for antiretroviral-naive individuals with HIV infection.

MA Fischl - AIDS (London, England), 1999 - europepmc.org
The choice of initial antiretroviral regimen for treating people infected with HIV is crucial to
successful long-term control of virus replication. Potent antiretroviral therapy substantially …

Is antiretroviral treatment of primary HIV infection clinically justified on the basis of current evidence?

DE Smith, BD Walker, DA Cooper, ES Rosenberg… - Aids, 2004 - journals.lww.com
When antiretroviral therapy first became available, it was hypothesized that the modest
clinical benefits seen in patients with advanced disease [1] would be more pronounced in …

Improved outcomes with earlier initiation of highly active antiretroviral therapy among human immunodeficiency virus–infected patients who achieve durable virologic …

TR Sterling, RE Chaisson, J Keruly… - The Journal of …, 2003 - academic.oup.com
On the basis of studies with relatively short follow-up, treatment guidelines currently
recommend that highly active antiretroviral therapy (HAART) be initiated in asymptomatic …

Antiretroviral therapy in the year 2000

KT Tashima, TP Flanigan - Infectious Disease Clinics of North America, 2000 - Elsevier
The treatment of HIV-infected patients has changed remarkably since early 1996 when more
potent agents became available and were used in combination therapy. Both clinical and …

Long-term follow-up of asymptomatic HIV-infected patients who discontinued antiretroviral therapy

ML Fernández Guerrero, P Rivas… - Clinical infectious …, 2005 - academic.oup.com
Background. Whether asymptomatic human immunodeficiency virus (HIV)–infected patients
can interrupt treatment remains unknown. Methods. We performed a prospective …