Current progress of genome editing in livestock
Historically, genetic engineering in livestock proved to be challenging. Without stable
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …
Application of genome-editing systems to enhance available pig resources for agriculture and biomedicine
Traditionally, genetic engineering in the pig was a challenging task. Genetic engineering of
somatic cells followed by somatic cell nuclear transfer (SCNT) could produce genetically …
somatic cells followed by somatic cell nuclear transfer (SCNT) could produce genetically …
Genome centric engineering using ZFNs, TALENs and CRISPR-Cas9 systems for trait improvement and disease control in Animals
Livestock is an essential life commodity in modern agriculture involving breeding and
maintenance. The farming practices have evolved mainly over the last century for …
maintenance. The farming practices have evolved mainly over the last century for …
Advances in genetic modification of farm animals using zinc-finger nucleases (ZFN)
B Petersen, H Niemann - Chromosome Research, 2015 - Springer
Genome editing tools (GET), including zinc-finger nucleases (ZFN), transcription activator-
like endonucleases (TALENS), and meganucleases possess long recognition sites and are …
like endonucleases (TALENS), and meganucleases possess long recognition sites and are …
Genome editing in livestock: Are we ready for a revolution in animal breeding industry?
J Ruan, J Xu, RY Chen-Tsai, K Li - Transgenic research, 2017 - Springer
Genome editing is a powerful technology that can efficiently alter the genome of organisms
to achieve targeted modification of endogenous genes and targeted integration of …
to achieve targeted modification of endogenous genes and targeted integration of …
Development of genome engineering technologies in cattle: from random to specific
SY Yum, KY Youn, WJ Choi, G Jang - Journal of animal science and …, 2018 - Springer
The production of transgenic farm animals (eg, cattle) via genome engineering for the gain
or loss of gene functions is an important undertaking. In the initial stages of genome …
or loss of gene functions is an important undertaking. In the initial stages of genome …
Basics of genome editing technology and its application in livestock species
B Petersen - Reproduction in Domestic Animals, 2017 - Wiley Online Library
Contents In the last decade, the research community has witnessed a blooming of targeted
genome editing tools and applications. Novel programmable DNA nucleases such as zinc …
genome editing tools and applications. Novel programmable DNA nucleases such as zinc …
Genome editing with engineered nucleases in economically important animals and plants: state of the art in the research pipeline
T Sovová, G Kerins, K Demnerová… - Current issues in molecular …, 2017 - mdpi.com
After induced mutagenesis and transgenesis, genome editing is the next step in the
development of breeding techniques. Genome editing using site-directed nucleases …
development of breeding techniques. Genome editing using site-directed nucleases …
Genome editing and genetic engineering in livestock for advancing agricultural and biomedical applications
Genetic modification of livestock has a longstanding and successful history, starting with
domestication several thousand years ago. Modern animal breeding strategies …
domestication several thousand years ago. Modern animal breeding strategies …
Use of gene-editing technology to introduce targeted modifications in pigs
Pigs are an important resource in agriculture and serve as a model for human diseases. Due
to their physiological and anatomical similarities with humans, pigs can recapitulate …
to their physiological and anatomical similarities with humans, pigs can recapitulate …