Effects of n-3 fatty acids on growth and survival of J774 macrophages

DJ Fyfe, M Abbey - Prostaglandins, Leukotrienes and Essential Fatty Acids …, 2000 - Elsevier
To further understand potential mechanisms underlying the protective effects of
eicosapentanoic acid (EPA) against atherosclerosis, J774 macrophages were used to …

In Vitro Inhibitory Effect of Docosahexaenoic and Eicosapentaenoic Acids on Human Endothelial Cell Production of Interleukin-6

B Khalfoun, JF Valentin, PY Sizaret, H Watier… - Endothelium, 1994 - Taylor & Francis
The interaction between lymphocytes, cytokines, and endothelial cells (EC) is a key step in
the inflammatory process. Interleukin-6 (IL-6), a pleiotropic cytokine in its effects, seems to …

Eicosapentaenoic acid and docosahexaenoic acid suppress the proliferation of vascular smooth muscle cells

T Shiina, T Terano, S Saito, Y Tamura, S Yoshida - Atherosclerosis, 1993 - Elsevier
Eicosapentaenoic acid, which is one of the n-3 polyunsaturated fatty acids (PUFA), is
reported to exert its antithrombotic and anti-atherogenic effect partly through the modulation …

[PDF][PDF] The effects of dietary lipid manipulation upon the production of reactive oxygen species by murine peritoneal macrophages

PC Calder - 1995 - researchgate.net
Macrophages have several roles in host defence, in the inflammatory response and in
regulating the immune response. These roles involve phagocytosis and the production of …

Orally administered eicosapentaenoic acid reduces and stabilizes atherosclerotic lesions in ApoE-deficient mice

M Matsumoto, M Sata, D Fukuda, K Tanaka, M Soma… - Atherosclerosis, 2008 - Elsevier
Accumulating evidence demonstrates that dietary intake of n-3 polyunsaturated fatty acids
(PUFAs) is associated with reduced incidence of cardiovascular events. However, the …

Effect of arachidonic and eicosapentaenoic acid metabolism on RAW 264.7 macrophage proliferation

D Nieves, JJ Moreno - Journal of cellular physiology, 2006 - Wiley Online Library
Abstract Prostaglandins (PGs) and leukotrienes (LTs) derived from arachidonic acid (AA) are
potent mediators of inflammation and cell proliferation. Dietary intake of eicosapentaenoic …

Pleiotropic, cardioprotective effects of omega-3 polyunsaturated fatty acids

PP Dimitrow, Jawien - Mini Reviews in Medicinal Chemistry, 2009 - benthamdirect.com
The cardioprotective effects of food rich in omega-3 (ω-3) polyunsaturated fatty acids (PUFA)
on cardiovascular risk has been of interest from the moment when a low rate of coronary …

Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages

JE McLaren, DR Michael, IA Guschina, JL Harwood… - Lipids, 2011 - Springer
There is evidence that long chain n-3 PUFA (such as from fish oils) provide atheroprotection
through, in part, changes in macrophage function although it has not been fully determined …

Docosahexaenoic and eicosapentaenoic acids inhibit in vitro human endothelial cell production of interleukin-6.

B Khalfoun, F Thibault, H Watier, P Bardos… - … medicine and biology, 1997 - europepmc.org
The interaction between lymphocytes, cytokines, and endothelial cells (EC) is a key step in
the inflammatory process. Interleukin-6 (IL-6) a pleiotropic cytokine in its effects, seems to be …

Combination of n-3 polyunsaturated fatty acids reduces atherogenesis in apolipoprotein E-deficient mice by inhibiting macrophage activation

A Takashima, D Fukuda, K Tanaka, Y Higashikuni… - Atherosclerosis, 2016 - Elsevier
Background and aims Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are
major components of n-3 polyunsaturated fatty acids (n-3 PUFAs) which inhibit …