Sepsis is the most common cause of death in critically ill patients and it may be associated
with multiorgan failure, including acute kidney injury (AKI). This situation can require acute …

Sepsis is the most common cause of death in critically ill patients and it may be associated
with multiorgan failure, including acute kidney injury (AKI). This situation can require acute …

Sepsis is the most common cause of death in critically ill patients and is associated with
multiorgan failure, including acute kidney injury (AKI). This situation can require acute renal …

A common cause of acute kidney injury (AKI) is sepsis, which makes appropriate dosing of
antibiotics in these patients essential. Drug dosing in critically ill patients with AKI, however …

Optimal dosing of antimicrobial therapy is pivotal to increase the likelihood of survival in
critically ill patients with sepsis. Drug exposure that maximizes bacterial killing, minimizes …

Introduction: Critically ill patients with acute kidney injury often require renal replacement
therapy and antibiotic therapy. Mortality rates are high in these patients, possibly due to …

Severe sepsis often leads to multiple organ dysfunction syndromes (MODS) with acute
kidney injury (AKI). AKI affects approximately, 35% of Intensive Care Unit patients, and most …

Increasing evidence suggests that antibiotic dosing in critically ill patients with acute kidney
injury (AKI) often does not achieve pharmacodynamic goals, and the continued high …

Background Acute kidney injury (AKI) is a potential complication of systemic infection.
Optimizing antimicrobial dosing in this dynamic state can be challenging with sub-or supra …

Acute kidney injury (AKI) is a common problem in hospitalized patients and is associated
with significant morbidity and mortality. Two large trials showed no benefit from increased …