In the dipteran Chironomus tentans, actin binds to hrp65, a nuclear protein associated with
mRNP complexes. Disruption of the actin–hrp65 interaction in vivo by the competing peptide …

Proper regulation of germline gene expression is essential for fertility and maintaining
species integrity. In the C. elegans germline, a diverse repertoire of regulatory pathways …

Background H19 was one of the earliest identified, and is the most studied, long noncoding
RNAs. It is presumed that H19 is essential for regulating development and disease …

A high expression level of the β-actin protein is required for important biological
mechanisms, such as maintaining cell shape, growth, and motility. Although the elevated …

MyoD regulates skeletal myogenesis. Since proteins associated with MyoD exert regulatory
functions, their identification is expected to contribute important insights into the mechanisms …

A number of regulatory factors are recruited to chromatin by specialized RNAs. Whether
RNA has a more general role in regulating the interaction of proteins with chromatin has not …

Transcription elongation rate influences cotranscriptional pre-mRNA maturation, but how
such kinetic coupling works is poorly understood. The formation of nonadenylated histone …

Establishment of segmental pattern in the Drosophila syncytial blastoderm embryo depends
on pair-rule transcriptional regulators. mRNA transcripts of pair-rule genes localise to the …

The regulation of gene expression via the histone code has, for the most part, revealed that
histone modifications cause the recruitment of adaptor proteins that indirectly regulate the …

Small RNAs derived from mature tRNAs, referred to as tRNA fragments or “tRFs,” are an
emerging class of regulatory RNAs with poorly understood functions. We recently identified …